Mitochondrial transplantation ameliorates rheumatoid arthritis by targeting abnormal CGAS-STING1 signaling activation, autophagosome accumulation, and necroptosis.

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Title: Mitochondrial transplantation ameliorates rheumatoid arthritis by targeting abnormal CGAS-STING1 signaling activation, autophagosome accumulation, and necroptosis.
Authors: Lee AR; Lab of Translational ImmunoMedicine, Catholic Research Institute of Medical Science, College of Medicine, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.; Department of Pathology, College of Medicine, The Catholic University of Korea, Seoul, South Korea., Woo JS; Lab of Translational ImmunoMedicine, Catholic Research Institute of Medical Science, College of Medicine, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea., Lee SY; Lab of Translational ImmunoMedicine, Catholic Research Institute of Medical Science, College of Medicine, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.; Department of Pathology, College of Medicine, The Catholic University of Korea, Seoul, South Korea., Shin Y; Department of Chemical and Biomolecular Engineering, Sogang University, Seoul, Korea.; Department of Biologics, Gachon University, Incheon, Republic of Korea., Jeon SB; Lab of Translational ImmunoMedicine, Catholic Research Institute of Medical Science, College of Medicine, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.; Department of Pathology, College of Medicine, The Catholic University of Korea, Seoul, South Korea.; Department of Biomedicine & Health Sciences, College of Medicine, The Catholic University of Korea, Seoul, Korea., Jo Y; Department of Chemical and Biomolecular Engineering, Sogang University, Seoul, Korea., Choi H; Department of Biomedicine & Health Sciences, College of Medicine, The Catholic University of Korea, Seoul, Korea.; Department of Microbiology, College of Medicine, The Catholic University of Korea, Seoul, Korea.; Catholic Hematopoietic Stem Cell Bank, College of Medicine, The Catholic University of Korea., Park SH; Rheumatism Research Center, College of Medicine, Catholic Research Institute of Medical Science, The Catholic University of Korea, Seoul, Korea., Kang T; Department of Chemical and Biomolecular Engineering, Sogang University, Seoul, Korea., Cho ML; Lab of Translational ImmunoMedicine, Catholic Research Institute of Medical Science, College of Medicine, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.; Department of Pathology, College of Medicine, The Catholic University of Korea, Seoul, South Korea.; Department of Biomedicine & Health Sciences, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Source: Autophagy [Autophagy] 2026 May; Vol. 22 (5), pp. 919-937. Date of Electronic Publication: 2026 Feb 11.
Publication Type: Journal Article
Journal Info: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101265188 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1554-8635 (Electronic) Linking ISSN: 15548627 NLM ISO Abbreviation: Autophagy Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1554-8635
DOI:10.1080/15548627.2026.2619283