Intranasal vaccines adjuvanted with Nexavant demonstrate robust protective efficacy by inducing both mucosal and systemic immunity in a murine model.

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Title: Intranasal vaccines adjuvanted with Nexavant demonstrate robust protective efficacy by inducing both mucosal and systemic immunity in a murine model.
Authors: Ko KH; Research and Development (R&D) Center, NA Vaccine Institute, Seoul, Republic of Korea., Bae HS; Research and Development (R&D) Center, NA Vaccine Institute, Seoul, Republic of Korea., Lee SM; Research and Development (R&D) Center, NA Vaccine Institute, Seoul, Republic of Korea., Park S; Department of Oral Microbiology and Immunology, and Dental Research Institute, School of Dentistry, Seoul National University, Seoul, Republic of Korea., Han SH; Department of Oral Microbiology and Immunology, and Dental Research Institute, School of Dentistry, Seoul National University, Seoul, Republic of Korea., Heo J; Vaccine Research and Development (R&D) Team, Central Institute, Il Yang Pharmaceutical, Yongin, Republic of Korea., Kim J; Vaccine Research and Development (R&D) Center, Eubiologics Co., Ltd, Chuncheon, Republic of Korea., Cho Y; Vaccine Research and Development (R&D) Center, Eubiologics Co., Ltd, Chuncheon, Republic of Korea., Kim DH; Research and Development (R&D) Center, NA Vaccine Institute, Seoul, Republic of Korea., Cha SB; Research and Development (R&D) Center, NA Vaccine Institute, Seoul, Republic of Korea.
Source: Frontiers in immunology [Front Immunol] 2026 Jan 16; Vol. 16, pp. 1745319. Date of Electronic Publication: 2026 Jan 16 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1664-3224
DOI:10.3389/fimmu.2025.1745319