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Intranasal vaccines adjuvanted with Nexavant demonstrate robust protective efficacy by inducing both mucosal and systemic immunity in a murine model.

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Title: Intranasal vaccines adjuvanted with Nexavant demonstrate robust protective efficacy by inducing both mucosal and systemic immunity in a murine model.
Authors: Ko KH; Research and Development (R&D) Center, NA Vaccine Institute, Seoul, Republic of Korea., Bae HS; Research and Development (R&D) Center, NA Vaccine Institute, Seoul, Republic of Korea., Lee SM; Research and Development (R&D) Center, NA Vaccine Institute, Seoul, Republic of Korea., Park S; Department of Oral Microbiology and Immunology, and Dental Research Institute, School of Dentistry, Seoul National University, Seoul, Republic of Korea., Han SH; Department of Oral Microbiology and Immunology, and Dental Research Institute, School of Dentistry, Seoul National University, Seoul, Republic of Korea., Heo J; Vaccine Research and Development (R&D) Team, Central Institute, Il Yang Pharmaceutical, Yongin, Republic of Korea., Kim J; Vaccine Research and Development (R&D) Center, Eubiologics Co., Ltd, Chuncheon, Republic of Korea., Cho Y; Vaccine Research and Development (R&D) Center, Eubiologics Co., Ltd, Chuncheon, Republic of Korea., Kim DH; Research and Development (R&D) Center, NA Vaccine Institute, Seoul, Republic of Korea., Cha SB; Research and Development (R&D) Center, NA Vaccine Institute, Seoul, Republic of Korea.
Source: Frontiers in immunology [Front Immunol] 2026 Jan 16; Vol. 16, pp. 1745319. Date of Electronic Publication: 2026 Jan 16 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Intranasal vaccines adjuvanted with Nexavant demonstrate robust protective efficacy by inducing both mucosal and systemic immunity in a murine model.
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  Data: <searchLink fieldCode="AU" term="%22Ko+KH%22">Ko KH</searchLink>; Research and Development (R&D) Center, NA Vaccine Institute, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Bae+HS%22">Bae HS</searchLink>; Research and Development (R&D) Center, NA Vaccine Institute, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+SM%22">Lee SM</searchLink>; Research and Development (R&D) Center, NA Vaccine Institute, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Park+S%22">Park S</searchLink>; Department of Oral Microbiology and Immunology, and Dental Research Institute, School of Dentistry, Seoul National University, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Han+SH%22">Han SH</searchLink>; Department of Oral Microbiology and Immunology, and Dental Research Institute, School of Dentistry, Seoul National University, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Heo+J%22">Heo J</searchLink>; Vaccine Research and Development (R&D) Team, Central Institute, Il Yang Pharmaceutical, Yongin, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+J%22">Kim J</searchLink>; Vaccine Research and Development (R&D) Center, Eubiologics Co., Ltd, Chuncheon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Cho+Y%22">Cho Y</searchLink>; Vaccine Research and Development (R&D) Center, Eubiologics Co., Ltd, Chuncheon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+DH%22">Kim DH</searchLink>; Research and Development (R&D) Center, NA Vaccine Institute, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Cha+SB%22">Cha SB</searchLink>; Research and Development (R&D) Center, NA Vaccine Institute, Seoul, Republic of Korea.
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  Data: <searchLink fieldCode="JN" term="%22101560960%22">Frontiers in immunology</searchLink> [Front Immunol] 2026 Jan 16; Vol. 16, pp. 1745319. <i>Date of Electronic Publication: </i>2026 Jan 16 (<i>Print Publication: </i>2025).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Frontiers+Research+Foundation]%22">Frontiers Research Foundation] </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101560960 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1664-3224 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2216643224%22">16643224 </searchLink><i>NLM ISO Abbreviation: </i>Front Immunol <i>Subsets: </i>MEDLINE
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        Value: 10.3389/fimmu.2025.1745319
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        Text: English
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              Text: 2026 Jan 16
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