Oral Semaglutide and Heart Failure Outcomes in Persons With Type 2 Diabetes: A Secondary Analysis of the SOUL Randomized Clinical Trial.
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| Title: | Oral Semaglutide and Heart Failure Outcomes in Persons With Type 2 Diabetes: A Secondary Analysis of the SOUL Randomized Clinical Trial. |
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| Authors: | Pop-Busui R; Division of Endocrinology, Diabetes and Clinical Nutrition, Department of Medicine, Oregon Health & Science University, Portland.; Division of Metabolism, Endocrinology and Diabetes, University of Michigan Medical School, Ann Arbor., Rasmussen S; Novo Nordisk A/S, Søborg, Denmark., Deanfield JE; Institute of Cardiovascular Sciences, University College London, London, England, United Kingdom., Buse JB; University of North Carolina School of Medicine, Chapel Hill., Marx N; Clinic for Cardiology, Angiology, and Intensive Care Medicine, RWTH Aachen University, University Hospital Aachen, Aachen, Germany., Mulvagh SL; Division of Cardiology, Department of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada., Inzucchi SE; Section of Endocrinology, Yale University School of Medicine, New Haven, Connecticut., Mann JFE; KfH Kidney Center, Munich, Germany.; Friedrich Alexander University of Erlangen, Erlangen, Germany., Emerson SS; Department of Biostatistics, School of Public Health, University of Washington, Seattle., Poulter NR; Imperial Clinical Trials Unit, Faculty of Medicine, Imperial College London, London, England, United Kingdom., Engelmann MDM; Novo Nordisk A/S, Søborg, Denmark., Hovingh GK; Novo Nordisk A/S, Søborg, Denmark., Bayer Tanggaard K; Novo Nordisk A/S, Søborg, Denmark., Birkenfeld AL; Department of Diabetology, Endocrinology and Nephrology, University Hospital Tübingen, Tübingen, Germany.; Institute for Diabetes Research and Metabolic Diseases of Helmholtz Munich, Eberhard Karls University of Tübingen, Tübingen, Germany.; German Center for Diabetes Research (DZD), Tübingen, Germany., Connelly KA; Keenan Research Centre for Biomedical Science, Departments of Medicine and Cardiology, St Michael's Hospital, University of Toronto, Toronto, Ontario, Canada., Haluzik M; Diabetes Centre, Institute for Clinical and Experimental Medicine, Prague, Czechia., Cavender MA; University of North Carolina School of Medicine, Chapel Hill., Kellerer M; Department of Diabetology and Endocrinology, Clinic for Internal Medicine, Marienhospital Stuttgart, Stuttgart, Germany., Jhund PS; British Heart Foundation Cardiovascular Research Centre, School of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow, Scotland, United Kingdom., Gregersen S; Steno Diabetes Center Aarhus, Department of Clinical Medicine, Aarhus University, Aarhus, Denmark., Nielsen OW; Novo Nordisk A/S, Søborg, Denmark., Lam CSP; National Heart Centre Singapore, Outram, Singapore.; Duke-National University of Singapore, Outram, Singapore., McGuire DK; Division of Cardiology, Department of Internal Medicine, University of Texas Southwestern Medical Center, Parkland Health System, Dallas. |
| Corporate Authors: | SOUL Study Group |
| Source: | JAMA internal medicine [JAMA Intern Med] 2026 Apr 01; Vol. 186 (4), pp. 426-436. |
| Publication Type: | Journal Article; Randomized Controlled Trial; Multicenter Study; Clinical Trial, Phase III |
| Journal Info: | Publisher: American Medical Association Country of Publication: United States NLM ID: 101589534 Publication Model: Print Cited Medium: Internet ISSN: 2168-6114 (Electronic) Linking ISSN: 21686106 NLM ISO Abbreviation: JAMA Intern Med Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2168-6114 |
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| DOI: | 10.1001/jamainternmed.2025.7774 |