Untargeted 1H NMR-based metabolomics unveils distinct circulating biochemical signatures between treatment-resistant and non-treatment-resistant schizophrenia patients: a pilot study.

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Title: Untargeted 1H NMR-based metabolomics unveils distinct circulating biochemical signatures between treatment-resistant and non-treatment-resistant schizophrenia patients: a pilot study.
Authors: Marino C; Department of Pharmacy, University of Salerno, Fisciano, Salerno, Italy., Zhang S; CEINGE Biotecnologie Avanzate 'Franco Salvatore', Naples, Italy., De Simone G; Section of Psychiatry, Laboratory of Translational and Molecular Psychiatry and Unit of Treatment-Resistant Psychosis, Department of Neuroscience, Reproductive Sciences and Odontostomatology, University Medical School of Naples 'Federico II', Naples, Italy., Grimaldi M; Department of Pharmacy, University of Salerno, Fisciano, Salerno, Italy., Di Maio A; CEINGE Biotecnologie Avanzate 'Franco Salvatore', Naples, Italy.; Department of Environmental, Biological and Pharmaceutical Sciences and Technologies, Università degli Studi della Campania 'Luigi Vanvitelli', Caserta, Italy., Iasevoli F; Section of Psychiatry, Laboratory of Translational and Molecular Psychiatry and Unit of Treatment-Resistant Psychosis, Department of Neuroscience, Reproductive Sciences and Odontostomatology, University Medical School of Naples 'Federico II', Naples, Italy., Errico F; CEINGE Biotecnologie Avanzate 'Franco Salvatore', Naples, Italy.; Department of Agricultural Sciences, University of Naples 'Federico II', Portici, Italy., D'Ursi AM; Department of Pharmacy, University of Salerno, Fisciano, Salerno, Italy., de Bartolomeis A; Section of Psychiatry, Laboratory of Translational and Molecular Psychiatry and Unit of Treatment-Resistant Psychosis, Department of Neuroscience, Reproductive Sciences and Odontostomatology, University Medical School of Naples 'Federico II', Naples, Italy. adebarto@unina.it., Usiello A; CEINGE Biotecnologie Avanzate 'Franco Salvatore', Naples, Italy. alessandro.usiello@unicampania.it.; Department of Environmental, Biological and Pharmaceutical Sciences and Technologies, Università degli Studi della Campania 'Luigi Vanvitelli', Caserta, Italy. alessandro.usiello@unicampania.it.
Source: Translational psychiatry [Transl Psychiatry] 2026 Feb 02; Vol. 16 (1). Date of Electronic Publication: 2026 Feb 02.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101562664 Publication Model: Electronic Cited Medium: Internet ISSN: 2158-3188 (Electronic) Linking ISSN: 21583188 NLM ISO Abbreviation: Transl Psychiatry Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Untargeted <superscript>1</superscript>H NMR-based metabolomics unveils distinct circulating biochemical signatures between treatment-resistant and non-treatment-resistant schizophrenia patients: a pilot study.
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  Data: <searchLink fieldCode="AU" term="%22Marino+C%22">Marino C</searchLink>; Department of Pharmacy, University of Salerno, Fisciano, Salerno, Italy.<br /><searchLink fieldCode="AU" term="%22Zhang+S%22">Zhang S</searchLink>; CEINGE Biotecnologie Avanzate 'Franco Salvatore', Naples, Italy.<br /><searchLink fieldCode="AU" term="%22De+Simone+G%22">De Simone G</searchLink>; Section of Psychiatry, Laboratory of Translational and Molecular Psychiatry and Unit of Treatment-Resistant Psychosis, Department of Neuroscience, Reproductive Sciences and Odontostomatology, University Medical School of Naples 'Federico II', Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Grimaldi+M%22">Grimaldi M</searchLink>; Department of Pharmacy, University of Salerno, Fisciano, Salerno, Italy.<br /><searchLink fieldCode="AU" term="%22Di+Maio+A%22">Di Maio A</searchLink>; CEINGE Biotecnologie Avanzate 'Franco Salvatore', Naples, Italy.; Department of Environmental, Biological and Pharmaceutical Sciences and Technologies, Università degli Studi della Campania 'Luigi Vanvitelli', Caserta, Italy.<br /><searchLink fieldCode="AU" term="%22Iasevoli+F%22">Iasevoli F</searchLink>; Section of Psychiatry, Laboratory of Translational and Molecular Psychiatry and Unit of Treatment-Resistant Psychosis, Department of Neuroscience, Reproductive Sciences and Odontostomatology, University Medical School of Naples 'Federico II', Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Errico+F%22">Errico F</searchLink>; CEINGE Biotecnologie Avanzate 'Franco Salvatore', Naples, Italy.; Department of Agricultural Sciences, University of Naples 'Federico II', Portici, Italy.<br /><searchLink fieldCode="AU" term="%22D'Ursi+AM%22">D'Ursi AM</searchLink>; Department of Pharmacy, University of Salerno, Fisciano, Salerno, Italy.<br /><searchLink fieldCode="AU" term="%22de+Bartolomeis+A%22">de Bartolomeis A</searchLink>; Section of Psychiatry, Laboratory of Translational and Molecular Psychiatry and Unit of Treatment-Resistant Psychosis, Department of Neuroscience, Reproductive Sciences and Odontostomatology, University Medical School of Naples 'Federico II', Naples, Italy. adebarto@unina.it.<br /><searchLink fieldCode="AU" term="%22Usiello+A%22">Usiello A</searchLink>; CEINGE Biotecnologie Avanzate 'Franco Salvatore', Naples, Italy. alessandro.usiello@unicampania.it.; Department of Environmental, Biological and Pharmaceutical Sciences and Technologies, Università degli Studi della Campania 'Luigi Vanvitelli', Caserta, Italy. alessandro.usiello@unicampania.it.
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  Data: <searchLink fieldCode="JN" term="%22101562664%22">Translational psychiatry</searchLink> [Transl Psychiatry] 2026 Feb 02; Vol. 16 (1). <i>Date of Electronic Publication: </i>2026 Feb 02.
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              Text: 2026 Feb 02
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