Stereoselective, sex-dependent 5-HT2A receptor modulation of cortical plasticity by MDMA in mice.

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Title: Stereoselective, sex-dependent 5-HT2A receptor modulation of cortical plasticity by MDMA in mice.
Authors: Gaines-Smith MC; Department of Pharmacology and Toxicology, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.; Biomedical Sciences Graduate Program, Virginia Commonwealth University School of Medicine, Richmond, VA, USA., Silverman JM; Department of Pharmacology and Toxicology, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.; Biomedical Sciences Graduate Program, Virginia Commonwealth University School of Medicine, Richmond, VA, USA., Fiorillo M; Department of Pharmacology and Toxicology, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.; Biomedical Sciences Graduate Program, Virginia Commonwealth University School of Medicine, Richmond, VA, USA., Younkin J; Department of Pharmacology and Toxicology, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.; Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA, USA.; Department of Biology, Virginia State University, Petersburg, VA, USA., Moore KN; Department of Pharmacology and Toxicology, Virginia Commonwealth University School of Medicine, Richmond, VA, USA., Maltman JL; Department of Pharmacology and Toxicology, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.; Biomedical Sciences Graduate Program, Virginia Commonwealth University School of Medicine, Richmond, VA, USA., de la Fuente Revenga M; Department of Pharmacology and Toxicology, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.; Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA, USA., Wolstenholme JT; Department of Pharmacology and Toxicology, Virginia Commonwealth University School of Medicine, Richmond, VA, USA., Glennon RA; Department of Medicinal Chemistry, Virginia Commonwealth University School of Pharmacy, Richmond, VA, USA., Dukat M; Department of Medicinal Chemistry, Virginia Commonwealth University School of Pharmacy, Richmond, VA, USA., González-Maeso J; Department of Pharmacology and Toxicology, Virginia Commonwealth University School of Medicine, Richmond, VA, USA. javier.maeso@vcuhealth.org.
Source: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology [Neuropsychopharmacology] 2026 May; Vol. 51 (6), pp. 1011-1022. Date of Electronic Publication: 2026 Feb 02.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8904907 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1740-634X (Electronic) Linking ISSN: 0893133X NLM ISO Abbreviation: Neuropsychopharmacology Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1740-634X
DOI:10.1038/s41386-025-02313-x