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Transient acute neuronal activation response caused by high concentrations of oligonucleotides in the cerebral spinal fluid.

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Title: Transient acute neuronal activation response caused by high concentrations of oligonucleotides in the cerebral spinal fluid.
Authors: Bravo-Hernandez M; Ionis Pharmaceuticals, Inc., Carlsbad, CA 92008, United States., Mazur C; Ionis Pharmaceuticals, Inc., Carlsbad, CA 92008, United States., Chen H; Ionis Pharmaceuticals, Inc., Carlsbad, CA 92008, United States., Fradkin L; Ionis Pharmaceuticals, Inc., Carlsbad, CA 92008, United States., Searcy J; Ionis Pharmaceuticals, Inc., Carlsbad, CA 92008, United States., Burel S; Ionis Pharmaceuticals, Inc., Carlsbad, CA 92008, United States., Kelly M; Ionis Pharmaceuticals, Inc., Carlsbad, CA 92008, United States., Bruening D; Ionis Pharmaceuticals, Inc., Carlsbad, CA 92008, United States., O'Rourke JG; Ionis Pharmaceuticals, Inc., Carlsbad, CA 92008, United States., Cai Y; Ionis Pharmaceuticals, Inc., Carlsbad, CA 92008, United States., Nguyen J; Ionis Pharmaceuticals, Inc., Carlsbad, CA 92008, United States., Berman-Booty L; Ionis Pharmaceuticals, Inc., Carlsbad, CA 92008, United States., Cummins L; Ionis Pharmaceuticals, Inc., Carlsbad, CA 92008, United States., Gaus H; Ionis Pharmaceuticals, Inc., Carlsbad, CA 92008, United States., Powers B; Ionis Pharmaceuticals, Inc., Carlsbad, CA 92008, United States., Zhao HT; Ionis Pharmaceuticals, Inc., Carlsbad, CA 92008, United States., Jafar-Nejad P; Ionis Pharmaceuticals, Inc., Carlsbad, CA 92008, United States., Henry S; Ionis Pharmaceuticals, Inc., Carlsbad, CA 92008, United States., Swayze EE; Ionis Pharmaceuticals, Inc., Carlsbad, CA 92008, United States., Kordasiewicz HB; Ionis Pharmaceuticals, Inc., Carlsbad, CA 92008, United States.
Source: Nucleic acids research [Nucleic Acids Res] 2026 Jan 22; Vol. 54 (3).
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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Description
ISSN:1362-4962
DOI:10.1093/nar/gkag057