Targeting TFAM K76 acetylation attenuates mitochondrial dysfunction and kidney injury in diabetic kidney disease.

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Title: Targeting TFAM K76 acetylation attenuates mitochondrial dysfunction and kidney injury in diabetic kidney disease.
Authors: Fu T; Shandong Provincial Key Medical and Health Laboratory of Cell Metabolism, Jinan Central Hospital, Shandong University, Jinan, 250013, Shandong, China.; Shandong Provincial Key Medical and Health Laboratory of Cell Metabolism, Central Hospital Affiliated to Shandong First Medical University, Jinan, 250013, Shandong, China., Sun S; Shandong Provincial Key Medical and Health Laboratory of Cell Metabolism, Central Hospital Affiliated to Shandong First Medical University, Jinan, 250013, Shandong, China., Wang Z; Shandong Provincial Key Medical and Health Laboratory of Cell Metabolism, Jinan Central Hospital, Shandong University, Jinan, 250013, Shandong, China.; Shandong Provincial Key Medical and Health Laboratory of Cell Metabolism, Central Hospital Affiliated to Shandong First Medical University, Jinan, 250013, Shandong, China., Zhao F; Department of Traditional Chinese Medicine, Central Hospital Affiliated to Shandong First Medical University, Jinan, 250013, Shandong, China., Zhen J; Department of Pathology, Cheeloo College of Medicine, Qilu Hospital of Shandong University, Jinan, 250012, Shandong, China., Ji X; Department of Pulmonary and Critical Care Medicine, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, 250021, Shandong, China.; Medical Science and Technology Innovation Center, Shandong First Medical University & Shandong Academy of Medical Sciences, Shandong, 250117, Jinan, China., Xue F; Shandong Provincial Key Medical and Health Laboratory of Cell Metabolism, Central Hospital Affiliated to Shandong First Medical University, Jinan, 250013, Shandong, China., Mu Q; Department of Pulmonary and Critical Care Medicine, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, 250021, Shandong, China.; Medical Science and Technology Innovation Center, Shandong First Medical University & Shandong Academy of Medical Sciences, Shandong, 250117, Jinan, China., Wang Y; Department of Pulmonary and Critical Care Medicine, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, 250021, Shandong, China.; Medical Science and Technology Innovation Center, Shandong First Medical University & Shandong Academy of Medical Sciences, Shandong, 250117, Jinan, China., Liu Y; Department of Pulmonary and Critical Care Medicine, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, 250021, Shandong, China. liuyishanyi@email.sdu.edu.cn.; Medical Science and Technology Innovation Center, Shandong First Medical University & Shandong Academy of Medical Sciences, Shandong, 250117, Jinan, China. liuyishanyi@email.sdu.edu.cn., Wan Q; Shandong Provincial Key Medical and Health Laboratory of Cell Metabolism, Jinan Central Hospital, Shandong University, Jinan, 250013, Shandong, China. wanqiang@sdu.edu.cn.; Shandong Provincial Key Medical and Health Laboratory of Cell Metabolism, Central Hospital Affiliated to Shandong First Medical University, Jinan, 250013, Shandong, China. wanqiang@sdu.edu.cn.
Source: Cardiovascular diabetology [Cardiovasc Diabetol] 2026 Feb 03; Vol. 25 (1). Date of Electronic Publication: 2026 Feb 03.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101147637 Publication Model: Electronic Cited Medium: Internet ISSN: 1475-2840 (Electronic) Linking ISSN: 14752840 NLM ISO Abbreviation: Cardiovasc Diabetol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1475-2840
DOI:10.1186/s12933-026-03089-0