The protective effect of ambroxol against cyclophosphamide-induced acute kidney injury involves Nrf2/HO-1 signaling upregulation and suppression of oxidative and inflammatory damage.
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| Title: | The protective effect of ambroxol against cyclophosphamide-induced acute kidney injury involves Nrf2/HO-1 signaling upregulation and suppression of oxidative and inflammatory damage. |
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| Authors: | Alruhaimi RS; Department of Biology, College of Science, Princess Nourah bint Abdulrahman University, Riyadh, 11671, Saudi Arabia., Hassanein EHM; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Al-Azhar University, Assiut, 71524, Egypt. emadhassanien@azhar.edu.eg., Alnasser SM; Department of Pharmacology and Toxicology, College of Pharmacy, Qassim University, Buraydah, 52571, Saudi Arabia., Althagafy HS; Division of Biochemistry, Department of Biological Sciences, Faculty of Science, University of Jeddah, Jeddah, 21589, Saudi Arabia., Sabry M; Department of Biochemistry and Molecular Biology, Faculty of Pharmacy, Al-Azhar University, Assiut, 71524, Egypt., Ahmed AA; Department of Biochemistry and Molecular Biology, Faculty of Pharmacy, Al-Azhar University, Assiut, 71524, Egypt., Mahmoud AM; Department of Life Sciences, Faculty of Science and Engineering, Manchester Metropolitan University, Manchester, M1 5GD, UK. a.mahmoud@mmu.ac.uk. |
| Source: | Naunyn-Schmiedeberg's archives of pharmacology [Naunyn Schmiedebergs Arch Pharmacol] 2026 Apr; Vol. 399 (7), pp. 10599-10614. Date of Electronic Publication: 2026 Feb 06. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0326264 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1912 (Electronic) Linking ISSN: 00281298 NLM ISO Abbreviation: Naunyn Schmiedebergs Arch Pharmacol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41644788 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: The protective effect of ambroxol against cyclophosphamide-induced acute kidney injury involves Nrf2/HO-1 signaling upregulation and suppression of oxidative and inflammatory damage. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Alruhaimi+RS%22">Alruhaimi RS</searchLink>; Department of Biology, College of Science, Princess Nourah bint Abdulrahman University, Riyadh, 11671, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Hassanein+EHM%22">Hassanein EHM</searchLink>; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Al-Azhar University, Assiut, 71524, Egypt. emadhassanien@azhar.edu.eg.<br /><searchLink fieldCode="AU" term="%22Alnasser+SM%22">Alnasser SM</searchLink>; Department of Pharmacology and Toxicology, College of Pharmacy, Qassim University, Buraydah, 52571, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Althagafy+HS%22">Althagafy HS</searchLink>; Division of Biochemistry, Department of Biological Sciences, Faculty of Science, University of Jeddah, Jeddah, 21589, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Sabry+M%22">Sabry M</searchLink>; Department of Biochemistry and Molecular Biology, Faculty of Pharmacy, Al-Azhar University, Assiut, 71524, Egypt.<br /><searchLink fieldCode="AU" term="%22Ahmed+AA%22">Ahmed AA</searchLink>; Department of Biochemistry and Molecular Biology, Faculty of Pharmacy, Al-Azhar University, Assiut, 71524, Egypt.<br /><searchLink fieldCode="AU" term="%22Mahmoud+AM%22">Mahmoud AM</searchLink>; Department of Life Sciences, Faculty of Science and Engineering, Manchester Metropolitan University, Manchester, M1 5GD, UK. a.mahmoud@mmu.ac.uk. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%220326264%22">Naunyn-Schmiedeberg's archives of pharmacology</searchLink> [Naunyn Schmiedebergs Arch Pharmacol] 2026 Apr; Vol. 399 (7), pp. 10599-10614. <i>Date of Electronic Publication: </i>2026 Feb 06. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+Verlag%22">Springer Verlag </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>0326264 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1432-1912 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200281298%22">00281298 </searchLink><i>NLM ISO Abbreviation: </i>Naunyn Schmiedebergs Arch Pharmacol <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41644788 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1007/s00210-025-04919-w Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 10599 Titles: – TitleFull: The protective effect of ambroxol against cyclophosphamide-induced acute kidney injury involves Nrf2/HO-1 signaling upregulation and suppression of oxidative and inflammatory damage. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Alruhaimi RS – PersonEntity: Name: NameFull: Hassanein EHM – PersonEntity: Name: NameFull: Alnasser SM – PersonEntity: Name: NameFull: Althagafy HS – PersonEntity: Name: NameFull: Sabry M – PersonEntity: Name: NameFull: Ahmed AA – PersonEntity: Name: NameFull: Mahmoud AM IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 04 Text: 2026 Apr Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1432-1912 Numbering: – Type: volume Value: 399 – Type: issue Value: 7 Titles: – TitleFull: Naunyn-Schmiedeberg's archives of pharmacology Type: main |
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