B-cell abundance in perivascular cuffs associates with local lesion activity in multiple sclerosis.

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Title: B-cell abundance in perivascular cuffs associates with local lesion activity in multiple sclerosis.
Authors: Engelenburg HJ; Neuroimmunology Research Group, Netherlands Institute for Neuroscience, Meibergdreef 47, 1105 BA, Amsterdam, The Netherlands. j.engelenburg@nin.knaw.nl., Westenbrink E; Neuroimmunology Research Group, Netherlands Institute for Neuroscience, Meibergdreef 47, 1105 BA, Amsterdam, The Netherlands., Runderkamp E; Neuroimmunology Research Group, Netherlands Institute for Neuroscience, Meibergdreef 47, 1105 BA, Amsterdam, The Netherlands., Marques AM; Department of Immunology, MS Center ErasMS, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands., van Luijn MM; Department of Immunology, MS Center ErasMS, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands., Hsiao CC; Neuroimmunology Research Group, Netherlands Institute for Neuroscience, Meibergdreef 47, 1105 BA, Amsterdam, The Netherlands., Huitinga I; Neuroimmunology Research Group, Netherlands Institute for Neuroscience, Meibergdreef 47, 1105 BA, Amsterdam, The Netherlands.; Swammerdam Institute for Life Sciences, University of Amsterdam, Amsterdam, The Netherlands., Hamann J; Neuroimmunology Research Group, Netherlands Institute for Neuroscience, Meibergdreef 47, 1105 BA, Amsterdam, The Netherlands.; Department of Experimental Immunology, Amsterdam Institute for Immunity and Infectious Diseases, Amsterdam University Medical Centers, Amsterdam, The Netherlands., Smolders J; Neuroimmunology Research Group, Netherlands Institute for Neuroscience, Meibergdreef 47, 1105 BA, Amsterdam, The Netherlands. j.j.f.m.smolders@erasmusmc.nl.; Department of Immunology, MS Center ErasMS, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands. j.j.f.m.smolders@erasmusmc.nl.; Department of Neurology, MS Center ErasMS, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands. j.j.f.m.smolders@erasmusmc.nl.
Source: Acta neuropathologica communications [Acta Neuropathol Commun] 2026 Feb 05; Vol. 14 (1). Date of Electronic Publication: 2026 Feb 05.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101610673 Publication Model: Electronic Cited Medium: Internet ISSN: 2051-5960 (Electronic) Linking ISSN: 20515960 NLM ISO Abbreviation: Acta Neuropathol Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2051-5960
DOI:10.1186/s40478-025-02208-4