Convergent Roles of Growth Differentiation Factor-15 (GDF-15) in Mechanotransduction, Vascular Disorganization, and Immune Suppression in Melanoma.

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Title: Convergent Roles of Growth Differentiation Factor-15 (GDF-15) in Mechanotransduction, Vascular Disorganization, and Immune Suppression in Melanoma.
Authors: Chen YC; Department of Molecular and Precision Medicine, The Pennsylvania State College of Medicine, Hershey, PA 17033, USA., Bollu VS; Department of Molecular and Precision Medicine, The Pennsylvania State College of Medicine, Hershey, PA 17033, USA., Kheirabadi S; Department of Chemical Engineering, The Pennsylvania State University, University Park, PA 16802, USA., LaPenna K; Department of Cell and Biological Systems, The Pennsylvania State College of Medicine, Hershey, PA 17033, USA., Berg A; Department of Public Health Sciences, The Pennsylvania State College of Medicine, Hershey, PA 17033., He P; Department of Cell and Biological Systems, The Pennsylvania State College of Medicine, Hershey, PA 17033, USA., Schell TD; Department of Cell and Biological Systems, The Pennsylvania State College of Medicine, Hershey, PA 17033, USA., Sheikhi A; Department of Chemical Engineering, The Pennsylvania State University, University Park, PA 16802, USA.; Department of Biomedical Engineering, The Pennsylvania State University, University Park, PA 16802, USA.; Department of Chemistry, The Pennsylvania State University, University Park, PA 16802, USA.; Huck Institutes of the Life Sciences, The Pennsylvania State University, University Park, PA 16802, USA.; Department of Neurosurgery, College of Medicine, The Pennsylvania State University, Hershey, PA 17033, USA., Tabdanov ED; Department of Cell and Biological Systems, The Pennsylvania State College of Medicine, Hershey, PA 17033, USA., Robertson GP; Department of Molecular and Precision Medicine, The Pennsylvania State College of Medicine, Hershey, PA 17033, USA.; Huck Institutes of the Life Sciences, The Pennsylvania State University, University Park, PA 16802, USA.; Departments of Pathology, The Pennsylvania State College of Medicine, Hershey, Hershey, PA 17033, USA.; Departments of Dermatology, The Pennsylvania State College of Medicine, Hershey, Hershey, PA 17033, USA.; Department of Surgery, The Pennsylvania State College of Medicine, Hershey, Hershey, PA 17033, USA.; Melanoma and Skin Cancer Center, Penn State Cancer Institute, The Pennsylvania State College of Medicine, Hershey, PA 17033, USA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2026 Jan 15. Date of Electronic Publication: 2026 Jan 15.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2692-8205
DOI:10.64898/2026.01.14.699463