Non-human primate preclinical model revealed the feasibility and short-term safety of iPSC-derived innate-like T cells in autologous transplantation.

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Title: Non-human primate preclinical model revealed the feasibility and short-term safety of iPSC-derived innate-like T cells in autologous transplantation.
Authors: Miyake Y; Shin Kaneko Laboratory, Department of Cell Growth and Differentiation, Center for iPS cell research and application (CiRA), Kyoto University, Kyoto, Japan., Iriguchi S; Shin Kaneko Laboratory, Department of Cell Growth and Differentiation, Center for iPS cell research and application (CiRA), Kyoto University, Kyoto, Japan., Kawana-Tachikawa A; AIDS Research Center, National Institute of Infectious Diseases, Japan Institute for Health Security, Tokyo, Japan., Kitayama S; Shin Kaneko Laboratory, Department of Cell Growth and Differentiation, Center for iPS cell research and application (CiRA), Kyoto University, Kyoto, Japan., Imai E; Shin Kaneko Laboratory, Department of Cell Growth and Differentiation, Center for iPS cell research and application (CiRA), Kyoto University, Kyoto, Japan., Taya K; Shin Kaneko Laboratory, Department of Cell Growth and Differentiation, Center for iPS cell research and application (CiRA), Kyoto University, Kyoto, Japan., Ishii H; Department of Latent Infection, National Institute of Infectious Diseases, Japan Institute for Health Security, Tokyo, Japan., Miura T; Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto, Japan., Sakawaki H; Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto, Japan., Matano T; National Institute of Infectious Diseases, Japan Institute for Health Security, Tokyo, Japan.; Institute of Medical Science, University of Tokyo, Tokyo, Japan., Kaneko S; Shin Kaneko Laboratory, Department of Cell Growth and Differentiation, Center for iPS cell research and application (CiRA), Kyoto University, Kyoto, Japan.
Source: Frontiers in immunology [Front Immunol] 2026 Jan 23; Vol. 16, pp. 1653275. Date of Electronic Publication: 2026 Jan 23 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1664-3224
DOI:10.3389/fimmu.2025.1653275