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Pharmacokinetics, Pharmacodynamics and Safety of Fultagliptin Benzoate Tablets, a DPP-4 Inhibitor, in Patients With Varying Degrees of Renal Insufficiency and Matched Healthy Volunteers: A Phase I Clinical Trial.

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Title: Pharmacokinetics, Pharmacodynamics and Safety of Fultagliptin Benzoate Tablets, a DPP-4 Inhibitor, in Patients With Varying Degrees of Renal Insufficiency and Matched Healthy Volunteers: A Phase I Clinical Trial.
Authors: Chen Y; Clinical Trial Center, West China Hospital, Sichuan University, 37 Guoxue Alley, Chengdu, 610041, Sichuan, China., Hu C; Clinical Trial Center, West China Hospital, Sichuan University, 37 Guoxue Alley, Chengdu, 610041, Sichuan, China., Cao X; Clinical Trial Center, West China Hospital, Sichuan University, 37 Guoxue Alley, Chengdu, 610041, Sichuan, China., Men Y; Clinical Trial Center, West China Hospital, Sichuan University, 37 Guoxue Alley, Chengdu, 610041, Sichuan, China., Wang Y; Clinical Trial Center, West China Hospital, Sichuan University, 37 Guoxue Alley, Chengdu, 610041, Sichuan, China., Zhang R; Shenzhen Salubris Pharmaceuticals Co., Ltd., Shenzhen, Guangdong, China., Guan H; Shenzhen Salubris Pharmaceuticals Co., Ltd., Shenzhen, Guangdong, China., Shi L; Shanghai Xihua Scientific Co., Ltd., Shanghai, China., Liu F; Department of Nephrology, West China Hospital, Sichuan University, Chengdu, China. liufangfh@163.com.; Laboratory of Diabetic Kidney Disease, Centre of Diabetes and Metabolism Research, West China Hospital, Sichuan University, 37 Guoxue Alley, Chengdu, 610041, Sichuan, China. liufangfh@163.com., Miao J; Clinical Trial Center, West China Hospital, Sichuan University, 37 Guoxue Alley, Chengdu, 610041, Sichuan, China. miaosiyi1971@163.com.
Source: Clinical pharmacokinetics [Clin Pharmacokinet] 2026 Apr; Vol. 65 (4), pp. 545-556. Date of Electronic Publication: 2026 Feb 09.
Publication Type: Journal Article; Clinical Trial, Phase I
Journal Info: Publisher: Country of Publication: Switzerland NLM ID: 7606849 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1179-1926 (Electronic) Linking ISSN: 03125963 NLM ISO Abbreviation: Clin Pharmacokinet Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1179-1926
DOI:10.1007/s40262-026-01622-8