Pulmonary fibroblasts activated by the addition of TNF-α and IL-4 enhance lymphangiogenic capacity and ameliorate lung fibrosis in an allogeneic rat model.

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Title: Pulmonary fibroblasts activated by the addition of TNF-α and IL-4 enhance lymphangiogenic capacity and ameliorate lung fibrosis in an allogeneic rat model.
Authors: Matsuoka Y; Department of Cardiology, Nagoya University Graduate School of Medicine, Nagoya, Japan.; Research & Development Department, LYMPHOGENiX Ltd, Covent Garden, London, England, United Kingdom., Shimizu Y; Department of Cardiology, Nagoya University Graduate School of Medicine, Nagoya, Japan., Sakamoto K; Department of Respiratory Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan., Matsuyama M; Department of Otorhinolaryngology, Juntendo University Faculty of Medicine., Murohara T; Department of Cardiology, Nagoya University Graduate School of Medicine, Nagoya, Japan., Iwamiya T; Research & Development Department, LYMPHOGENiX Ltd, Covent Garden, London, England, United Kingdom.; Institute for Advanced Biosciences, Keio University, Tsuruoka, Yamagata, Japan.
Source: PloS one [PLoS One] 2026 Feb 10; Vol. 21 (2), pp. e0342528. Date of Electronic Publication: 2026 Feb 10 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1932-6203
DOI:10.1371/journal.pone.0342528