Programmable local immunochemotherapy for triple-negative breast cancer via spatiotemporally controlled release of CpG oligodeoxynucleotides, gemcitabine, and paclitaxel.

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Title: Programmable local immunochemotherapy for triple-negative breast cancer via spatiotemporally controlled release of CpG oligodeoxynucleotides, gemcitabine, and paclitaxel.
Authors: Hsieh CH; Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.; Department of Emergency Medicine, En Chu Kong Hospital, Sanxia, New Taipei City, Taiwan., Hsu MY; Department of Medical Imaging and Intervention, Chang Gung Memorial Hospital, Linkou, Taiwan.; Department of Mechanical Engineering, Chang Gung University, Taoyuan, Taiwan., Lin CF; Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.; Department of Microbiology and Immunology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.; Graduate Institute of Medical Sciences, Taipei Medical University, Taipei, Taiwan., Liu CC; The School of Public Health and Medical Technology, Xiamen Medical College, Xiamen, Fujian, China.; Engineering Research Center of Natural Cosmeceuticals College of Fujian Province, Xiamen Medical College, Fujian, China., Kuo YH; Department of Mechanical Engineering, Chang Gung University, Taoyuan, Taiwan., Huang YT; Department of Diagnostic Radiology, Chang Gung Memorial Hospital, Keelung, Taiwan., Chen WY; Department of Pathology, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan.; Department of Pathology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan., Liu SJ; Department of Mechanical Engineering, Chang Gung University, Taoyuan, Taiwan. shihjung@mail.cgu.edu.tw.; Department of Orthopedic Surgery, Bone and Joint Research Center, Chang Gung Memorial Hospital, Taoyuan, Taiwan. shihjung@mail.cgu.edu.tw., Lee WJ; Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan. wjlee@tmu.edu.tw.; Department of Urology, School of Medicine, College of Medicine and TMU Research Center of Urology and Kidney (TMU-RCUK), Taipei Medical University, Taipei, Taiwan. wjlee@tmu.edu.tw.; Department of Medical Education and Research, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan. wjlee@tmu.edu.tw.
Source: NPJ breast cancer [NPJ Breast Cancer] 2026 Feb 13; Vol. 12 (1). Date of Electronic Publication: 2026 Feb 13.
Publication Type: Journal Article
Journal Info: Publisher: Breast Cancer Research Foundation Country of Publication: United States NLM ID: 101674891 Publication Model: Electronic Cited Medium: Print ISSN: 2374-4677 (Print) Linking ISSN: 23744677 NLM ISO Abbreviation: NPJ Breast Cancer Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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ISSN:2374-4677
DOI:10.1038/s41523-026-00910-7