Human umbilical mesenchymal stem cell-derived mitochondria transplantation suppresses sFLT-1 secretion by regulating calcineurin-NFAT-dependent pathways in angiotensin II-induced preeclampsia rats.

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Title: Human umbilical mesenchymal stem cell-derived mitochondria transplantation suppresses sFLT-1 secretion by regulating calcineurin-NFAT-dependent pathways in angiotensin II-induced preeclampsia rats.
Authors: Cui HX; Department of Medical Cosmetology and Plastic Surgery, Shandong Provincial Maternal and Child Health Care Hospital Affiliated to Qingdao University, Jinan, Shandong, China.; Department of Physiology & Biomedical Sciences, Ischemic/Hypoxic Disease Institute, Seoul National University College of Medicine, Seoul, Republic of Korea., Liu JX; Department of Physiology & Biomedical Sciences, Ischemic/Hypoxic Disease Institute, Seoul National University College of Medicine, Seoul, Republic of Korea., Kang YC; Paean Biotechnology, Inc., 5 Samil-Daero 8-Gil, Jung-Gu, Seoul, 04552, Republic of Korea. Kangyc@paeanbio.com., Han K; Paean Biotechnology, Inc., 5 Samil-Daero 8-Gil, Jung-Gu, Seoul, 04552, Republic of Korea., Lee HK; Paean Biotechnology, Inc., 5 Samil-Daero 8-Gil, Jung-Gu, Seoul, 04552, Republic of Korea., Kim CH; Paean Biotechnology, Inc., 5 Samil-Daero 8-Gil, Jung-Gu, Seoul, 04552, Republic of Korea., Zhang YH; Department of Physiology & Biomedical Sciences, Ischemic/Hypoxic Disease Institute, Seoul National University College of Medicine, Seoul, Republic of Korea. yinzhang@snu.ac.kr.; Yanbian University Hospital, Yanji, China. yinzhang@snu.ac.kr.
Source: Stem cell research & therapy [Stem Cell Res Ther] 2026 Feb 13; Vol. 17 (1). Date of Electronic Publication: 2026 Feb 13.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101527581 Publication Model: Electronic Cited Medium: Internet ISSN: 1757-6512 (Electronic) Linking ISSN: 17576512 NLM ISO Abbreviation: Stem Cell Res Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1757-6512
DOI:10.1186/s13287-026-04930-9