Human umbilical mesenchymal stem cell-derived mitochondria transplantation suppresses sFLT-1 secretion by regulating calcineurin-NFAT-dependent pathways in angiotensin II-induced preeclampsia rats.

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Title: Human umbilical mesenchymal stem cell-derived mitochondria transplantation suppresses sFLT-1 secretion by regulating calcineurin-NFAT-dependent pathways in angiotensin II-induced preeclampsia rats.
Authors: Cui HX; Department of Medical Cosmetology and Plastic Surgery, Shandong Provincial Maternal and Child Health Care Hospital Affiliated to Qingdao University, Jinan, Shandong, China.; Department of Physiology & Biomedical Sciences, Ischemic/Hypoxic Disease Institute, Seoul National University College of Medicine, Seoul, Republic of Korea., Liu JX; Department of Physiology & Biomedical Sciences, Ischemic/Hypoxic Disease Institute, Seoul National University College of Medicine, Seoul, Republic of Korea., Kang YC; Paean Biotechnology, Inc., 5 Samil-Daero 8-Gil, Jung-Gu, Seoul, 04552, Republic of Korea. Kangyc@paeanbio.com., Han K; Paean Biotechnology, Inc., 5 Samil-Daero 8-Gil, Jung-Gu, Seoul, 04552, Republic of Korea., Lee HK; Paean Biotechnology, Inc., 5 Samil-Daero 8-Gil, Jung-Gu, Seoul, 04552, Republic of Korea., Kim CH; Paean Biotechnology, Inc., 5 Samil-Daero 8-Gil, Jung-Gu, Seoul, 04552, Republic of Korea., Zhang YH; Department of Physiology & Biomedical Sciences, Ischemic/Hypoxic Disease Institute, Seoul National University College of Medicine, Seoul, Republic of Korea. yinzhang@snu.ac.kr.; Yanbian University Hospital, Yanji, China. yinzhang@snu.ac.kr.
Source: Stem cell research & therapy [Stem Cell Res Ther] 2026 Feb 13; Vol. 17 (1). Date of Electronic Publication: 2026 Feb 13.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101527581 Publication Model: Electronic Cited Medium: Internet ISSN: 1757-6512 (Electronic) Linking ISSN: 17576512 NLM ISO Abbreviation: Stem Cell Res Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Human umbilical mesenchymal stem cell-derived mitochondria transplantation suppresses sFLT-1 secretion by regulating calcineurin-NFAT-dependent pathways in angiotensin II-induced preeclampsia rats.
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  Data: <searchLink fieldCode="AU" term="%22Cui+HX%22">Cui HX</searchLink>; Department of Medical Cosmetology and Plastic Surgery, Shandong Provincial Maternal and Child Health Care Hospital Affiliated to Qingdao University, Jinan, Shandong, China.; Department of Physiology & Biomedical Sciences, Ischemic/Hypoxic Disease Institute, Seoul National University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Liu+JX%22">Liu JX</searchLink>; Department of Physiology & Biomedical Sciences, Ischemic/Hypoxic Disease Institute, Seoul National University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kang+YC%22">Kang YC</searchLink>; Paean Biotechnology, Inc., 5 Samil-Daero 8-Gil, Jung-Gu, Seoul, 04552, Republic of Korea. Kangyc@paeanbio.com.<br /><searchLink fieldCode="AU" term="%22Han+K%22">Han K</searchLink>; Paean Biotechnology, Inc., 5 Samil-Daero 8-Gil, Jung-Gu, Seoul, 04552, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+HK%22">Lee HK</searchLink>; Paean Biotechnology, Inc., 5 Samil-Daero 8-Gil, Jung-Gu, Seoul, 04552, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+CH%22">Kim CH</searchLink>; Paean Biotechnology, Inc., 5 Samil-Daero 8-Gil, Jung-Gu, Seoul, 04552, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Zhang+YH%22">Zhang YH</searchLink>; Department of Physiology & Biomedical Sciences, Ischemic/Hypoxic Disease Institute, Seoul National University College of Medicine, Seoul, Republic of Korea. yinzhang@snu.ac.kr.; Yanbian University Hospital, Yanji, China. yinzhang@snu.ac.kr.
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  Data: <searchLink fieldCode="JN" term="%22101527581%22">Stem cell research & therapy</searchLink> [Stem Cell Res Ther] 2026 Feb 13; Vol. 17 (1). <i>Date of Electronic Publication: </i>2026 Feb 13.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101527581 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1757-6512 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2217576512%22">17576512 </searchLink><i>NLM ISO Abbreviation: </i>Stem Cell Res Ther <i>Subsets: </i>MEDLINE
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      – Type: doi
        Value: 10.1186/s13287-026-04930-9
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      – Code: eng
        Text: English
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      – TitleFull: Human umbilical mesenchymal stem cell-derived mitochondria transplantation suppresses sFLT-1 secretion by regulating calcineurin-NFAT-dependent pathways in angiotensin II-induced preeclampsia rats.
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            NameFull: Cui HX
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            – D: 13
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              Text: 2026 Feb 13
              Type: published
              Y: 2026
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