Effect of clinically relevant iron oxide nanoparticles on macrophage polarization, tumor growth and tumor microenvironment modulation.

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Title: Effect of clinically relevant iron oxide nanoparticles on macrophage polarization, tumor growth and tumor microenvironment modulation.
Authors: Roemhild K; Institute of Experimental Molecular Imaging, University Hospital RWTH Aachen, Aachen, Germany; Institute of Pathology, University Hospital RWTH Aachen, Aachen, Germany., Li Y; Institute of Experimental Molecular Imaging, University Hospital RWTH Aachen, Aachen, Germany., Barmin RA; Institute of Experimental Molecular Imaging, University Hospital RWTH Aachen, Aachen, Germany., Dadfar SM; Institute of Experimental Molecular Imaging, University Hospital RWTH Aachen, Aachen, Germany; Ardena Oss, Kloosterstraat 9, 5349 AB Oss, the Netherlands., Savina E; Institute of Experimental Molecular Imaging, University Hospital RWTH Aachen, Aachen, Germany., Lindelauf K; Institute of Experimental Molecular Imaging, University Hospital RWTH Aachen, Aachen, Germany., Moeckel D; Institute of Experimental Molecular Imaging, University Hospital RWTH Aachen, Aachen, Germany., Rama E; Institute of Experimental Molecular Imaging, University Hospital RWTH Aachen, Aachen, Germany., Lemainque T; Institute of Experimental Molecular Imaging, University Hospital RWTH Aachen, Aachen, Germany; Department of Diagnostic and Interventional Radiology, Medical Faculty, University Hospital RWTH Aachen, Aachen, Germany., von Maltzahn F; Institute of Experimental Molecular Imaging, University Hospital RWTH Aachen, Aachen, Germany., Thoröe-Boveleth S; Institute of Occupational, Social and Environmental Medicine, University Hospital RWTH Aachen, Aachen, Germany., Pola R; Institute of Macromolecular Chemistry, Czech Academy of Sciences, Prague, Czech Republic., Etrych T; Institute of Macromolecular Chemistry, Czech Academy of Sciences, Prague, Czech Republic., Knuechel-Clarke R; Institute of Pathology, University Hospital RWTH Aachen, Aachen, Germany., Boor P; Institute of Pathology, University Hospital RWTH Aachen, Aachen, Germany; Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD), Aachen, Germany., Kraus T; Institute of Occupational, Social and Environmental Medicine, University Hospital RWTH Aachen, Aachen, Germany., Schulz V; Institute for Imaging and Computer Vision, University Hospital RWTH Aachen, Aachen, Germany., Grimm J; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Kiessling F; Institute of Experimental Molecular Imaging, University Hospital RWTH Aachen, Aachen, Germany., von Stillfried S; Institute of Pathology, University Hospital RWTH Aachen, Aachen, Germany; Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD), Aachen, Germany., Pallares RM; Institute of Experimental Molecular Imaging, University Hospital RWTH Aachen, Aachen, Germany. Electronic address: rmoltopallar@ukaachen.de., Lammers T; Institute of Experimental Molecular Imaging, University Hospital RWTH Aachen, Aachen, Germany; Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD), Aachen, Germany. Electronic address: tlammers@ukaachen.de.
Source: Journal of controlled release : official journal of the Controlled Release Society [J Control Release] 2026 Apr 10; Vol. 392, pp. 114726. Date of Electronic Publication: 2026 Feb 13.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Science Publishers Country of Publication: Netherlands NLM ID: 8607908 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4995 (Electronic) Linking ISSN: 01683659 NLM ISO Abbreviation: J Control Release Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1873-4995
DOI:10.1016/j.jconrel.2026.114726