Effect of clinically relevant iron oxide nanoparticles on macrophage polarization, tumor growth and tumor microenvironment modulation.

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Title: Effect of clinically relevant iron oxide nanoparticles on macrophage polarization, tumor growth and tumor microenvironment modulation.
Authors: Roemhild K; Institute of Experimental Molecular Imaging, University Hospital RWTH Aachen, Aachen, Germany; Institute of Pathology, University Hospital RWTH Aachen, Aachen, Germany., Li Y; Institute of Experimental Molecular Imaging, University Hospital RWTH Aachen, Aachen, Germany., Barmin RA; Institute of Experimental Molecular Imaging, University Hospital RWTH Aachen, Aachen, Germany., Dadfar SM; Institute of Experimental Molecular Imaging, University Hospital RWTH Aachen, Aachen, Germany; Ardena Oss, Kloosterstraat 9, 5349 AB Oss, the Netherlands., Savina E; Institute of Experimental Molecular Imaging, University Hospital RWTH Aachen, Aachen, Germany., Lindelauf K; Institute of Experimental Molecular Imaging, University Hospital RWTH Aachen, Aachen, Germany., Moeckel D; Institute of Experimental Molecular Imaging, University Hospital RWTH Aachen, Aachen, Germany., Rama E; Institute of Experimental Molecular Imaging, University Hospital RWTH Aachen, Aachen, Germany., Lemainque T; Institute of Experimental Molecular Imaging, University Hospital RWTH Aachen, Aachen, Germany; Department of Diagnostic and Interventional Radiology, Medical Faculty, University Hospital RWTH Aachen, Aachen, Germany., von Maltzahn F; Institute of Experimental Molecular Imaging, University Hospital RWTH Aachen, Aachen, Germany., Thoröe-Boveleth S; Institute of Occupational, Social and Environmental Medicine, University Hospital RWTH Aachen, Aachen, Germany., Pola R; Institute of Macromolecular Chemistry, Czech Academy of Sciences, Prague, Czech Republic., Etrych T; Institute of Macromolecular Chemistry, Czech Academy of Sciences, Prague, Czech Republic., Knuechel-Clarke R; Institute of Pathology, University Hospital RWTH Aachen, Aachen, Germany., Boor P; Institute of Pathology, University Hospital RWTH Aachen, Aachen, Germany; Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD), Aachen, Germany., Kraus T; Institute of Occupational, Social and Environmental Medicine, University Hospital RWTH Aachen, Aachen, Germany., Schulz V; Institute for Imaging and Computer Vision, University Hospital RWTH Aachen, Aachen, Germany., Grimm J; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Kiessling F; Institute of Experimental Molecular Imaging, University Hospital RWTH Aachen, Aachen, Germany., von Stillfried S; Institute of Pathology, University Hospital RWTH Aachen, Aachen, Germany; Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD), Aachen, Germany., Pallares RM; Institute of Experimental Molecular Imaging, University Hospital RWTH Aachen, Aachen, Germany. Electronic address: rmoltopallar@ukaachen.de., Lammers T; Institute of Experimental Molecular Imaging, University Hospital RWTH Aachen, Aachen, Germany; Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD), Aachen, Germany. Electronic address: tlammers@ukaachen.de.
Source: Journal of controlled release : official journal of the Controlled Release Society [J Control Release] 2026 Apr 10; Vol. 392, pp. 114726. Date of Electronic Publication: 2026 Feb 13.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Science Publishers Country of Publication: Netherlands NLM ID: 8607908 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4995 (Electronic) Linking ISSN: 01683659 NLM ISO Abbreviation: J Control Release Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Effect of clinically relevant iron oxide nanoparticles on macrophage polarization, tumor growth and tumor microenvironment modulation.
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  Data: <searchLink fieldCode="AU" term="%22Roemhild+K%22">Roemhild K</searchLink>; Institute of Experimental Molecular Imaging, University Hospital RWTH Aachen, Aachen, Germany; Institute of Pathology, University Hospital RWTH Aachen, Aachen, Germany.<br /><searchLink fieldCode="AU" term="%22Li+Y%22">Li Y</searchLink>; Institute of Experimental Molecular Imaging, University Hospital RWTH Aachen, Aachen, Germany.<br /><searchLink fieldCode="AU" term="%22Barmin+RA%22">Barmin RA</searchLink>; Institute of Experimental Molecular Imaging, University Hospital RWTH Aachen, Aachen, Germany.<br /><searchLink fieldCode="AU" term="%22Dadfar+SM%22">Dadfar SM</searchLink>; Institute of Experimental Molecular Imaging, University Hospital RWTH Aachen, Aachen, Germany; Ardena Oss, Kloosterstraat 9, 5349 AB Oss, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Savina+E%22">Savina E</searchLink>; Institute of Experimental Molecular Imaging, University Hospital RWTH Aachen, Aachen, Germany.<br /><searchLink fieldCode="AU" term="%22Lindelauf+K%22">Lindelauf K</searchLink>; Institute of Experimental Molecular Imaging, University Hospital RWTH Aachen, Aachen, Germany.<br /><searchLink fieldCode="AU" term="%22Moeckel+D%22">Moeckel D</searchLink>; Institute of Experimental Molecular Imaging, University Hospital RWTH Aachen, Aachen, Germany.<br /><searchLink fieldCode="AU" term="%22Rama+E%22">Rama E</searchLink>; Institute of Experimental Molecular Imaging, University Hospital RWTH Aachen, Aachen, Germany.<br /><searchLink fieldCode="AU" term="%22Lemainque+T%22">Lemainque T</searchLink>; Institute of Experimental Molecular Imaging, University Hospital RWTH Aachen, Aachen, Germany; Department of Diagnostic and Interventional Radiology, Medical Faculty, University Hospital RWTH Aachen, Aachen, Germany.<br /><searchLink fieldCode="AU" term="%22von+Maltzahn+F%22">von Maltzahn F</searchLink>; Institute of Experimental Molecular Imaging, University Hospital RWTH Aachen, Aachen, Germany.<br /><searchLink fieldCode="AU" term="%22Thoröe-Boveleth+S%22">Thoröe-Boveleth S</searchLink>; Institute of Occupational, Social and Environmental Medicine, University Hospital RWTH Aachen, Aachen, Germany.<br /><searchLink fieldCode="AU" term="%22Pola+R%22">Pola R</searchLink>; Institute of Macromolecular Chemistry, Czech Academy of Sciences, Prague, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Etrych+T%22">Etrych T</searchLink>; Institute of Macromolecular Chemistry, Czech Academy of Sciences, Prague, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Knuechel-Clarke+R%22">Knuechel-Clarke R</searchLink>; Institute of Pathology, University Hospital RWTH Aachen, Aachen, Germany.<br /><searchLink fieldCode="AU" term="%22Boor+P%22">Boor P</searchLink>; Institute of Pathology, University Hospital RWTH Aachen, Aachen, Germany; Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD), Aachen, Germany.<br /><searchLink fieldCode="AU" term="%22Kraus+T%22">Kraus T</searchLink>; Institute of Occupational, Social and Environmental Medicine, University Hospital RWTH Aachen, Aachen, Germany.<br /><searchLink fieldCode="AU" term="%22Schulz+V%22">Schulz V</searchLink>; Institute for Imaging and Computer Vision, University Hospital RWTH Aachen, Aachen, Germany.<br /><searchLink fieldCode="AU" term="%22Grimm+J%22">Grimm J</searchLink>; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Kiessling+F%22">Kiessling F</searchLink>; Institute of Experimental Molecular Imaging, University Hospital RWTH Aachen, Aachen, Germany.<br /><searchLink fieldCode="AU" term="%22von+Stillfried+S%22">von Stillfried S</searchLink>; Institute of Pathology, University Hospital RWTH Aachen, Aachen, Germany; Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD), Aachen, Germany.<br /><searchLink fieldCode="AU" term="%22Pallares+RM%22">Pallares RM</searchLink>; Institute of Experimental Molecular Imaging, University Hospital RWTH Aachen, Aachen, Germany. Electronic address: rmoltopallar@ukaachen.de.<br /><searchLink fieldCode="AU" term="%22Lammers+T%22">Lammers T</searchLink>; Institute of Experimental Molecular Imaging, University Hospital RWTH Aachen, Aachen, Germany; Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD), Aachen, Germany. Electronic address: tlammers@ukaachen.de.
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  Data: <searchLink fieldCode="JN" term="%228607908%22">Journal of controlled release : official journal of the Controlled Release Society</searchLink> [J Control Release] 2026 Apr 10; Vol. 392, pp. 114726. <i>Date of Electronic Publication: </i>2026 Feb 13.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Science+Publishers%22">Elsevier Science Publishers </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>8607908 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1873-4995 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2201683659%22">01683659 </searchLink><i>NLM ISO Abbreviation: </i>J Control Release <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.jconrel.2026.114726
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