Tumor-reactive TCRs within exhausted TILs reveal cancer type-specific immune landscapes in renal cell carcinoma.
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| Title: | Tumor-reactive TCRs within exhausted TILs reveal cancer type-specific immune landscapes in renal cell carcinoma. |
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| Authors: | Komahashi M; Division of Cancer Immunotherapy, Kanagawa Cancer Center Research Institute, Yokohama, Japan.; Cancer Vaccine and Immunotherapy Center, Kanagawa Cancer Center Research Institute, Yokohama, Japan.; Department of Pediatric Surgery, Nihon University School of Medicine, Tokyo, Japan., Horaguchi S; Division of Cancer Immunotherapy, Kanagawa Cancer Center Research Institute, Yokohama, Japan.; Cancer Vaccine and Immunotherapy Center, Kanagawa Cancer Center Research Institute, Yokohama, Japan.; Department of Pediatric Surgery, Nihon University School of Medicine, Tokyo, Japan., Tsuji K; Division of Cancer Immunotherapy, Kanagawa Cancer Center Research Institute, Yokohama, Japan.; Cancer Vaccine and Immunotherapy Center, Kanagawa Cancer Center Research Institute, Yokohama, Japan., Hoshino D; Cancer Biology Division, Kanagawa Cancer Center Research Institute, Yokohama, Japan., Kishida T; Department of Urology, Kanagawa Cancer Center, Yokohama, Japan., Usui K; Department of Urology, Kanagawa Cancer Center, Yokohama, Japan., Nakaigawa N; Department of Urology, Kanagawa Cancer Center, Yokohama, Japan., Sato S; Molecular Pathology and Genetics Division, Kanagawa Cancer Center Research Institute, Yokohama, Japan.; Morphological Information Laboratory, Kanagawa Cancer Center Research Institute, Yokohama, Japan., Hamana H; Department of Immunology, Faculty of Medicine, Academic Assembly, University of Toyama, Toyama, Japan., Kishi H; Department of Immunology, Faculty of Medicine, Academic Assembly, University of Toyama, Toyama, Japan., Wei F; Division of Cancer Immunotherapy, Kanagawa Cancer Center Research Institute, Yokohama, Japan.; Cancer Vaccine and Immunotherapy Center, Kanagawa Cancer Center Research Institute, Yokohama, Japan., Mano Y; Division of Cancer Immunotherapy, Kanagawa Cancer Center Research Institute, Yokohama, Japan.; Cancer Vaccine and Immunotherapy Center, Kanagawa Cancer Center Research Institute, Yokohama, Japan., Kouro T; Division of Cancer Immunotherapy, Kanagawa Cancer Center Research Institute, Yokohama, Japan.; Cancer Vaccine and Immunotherapy Center, Kanagawa Cancer Center Research Institute, Yokohama, Japan., Uehara S; Department of Pediatric Surgery, Nihon University School of Medicine, Tokyo, Japan., Sasada T; Division of Cancer Immunotherapy, Kanagawa Cancer Center Research Institute, Yokohama, Japan.; Cancer Vaccine and Immunotherapy Center, Kanagawa Cancer Center Research Institute, Yokohama, Japan. |
| Source: | Frontiers in immunology [Front Immunol] 2026 Jan 29; Vol. 17, pp. 1729388. Date of Electronic Publication: 2026 Jan 29 (Print Publication: 2026). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1664-3224 |
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| DOI: | 10.3389/fimmu.2026.1729388 |
