Multimorbidity phenotypes and associated characteristics in severe asthma: an observational study of European severe asthma registries.

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Title: Multimorbidity phenotypes and associated characteristics in severe asthma: an observational study of European severe asthma registries.
Authors: Freeman A; School of Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, UK.; National Institute for Health Research (NIHR) Southampton Biomedical Research Centre at University Hospital Southampton NHS Foundation Trust, Southampton, UK.; Respiratory Medicine Department, University Hospital Southampton NHS Foundation Trust, Southampton, UK., Rink S; Department of Pulmonary Diseases and Allergy, University Medical Centre Ljubljana, Slovenia.; Faculty of Medicine, University of Ljubljana, Slovenia., Bansal AT; Acclarogen Ltd, St John's Innovation Centre, Cambridge, UK., Frankemölle B; European Lung Foundation, UK., Singh M; European Lung Foundation, UK., Sont JK; Dept of Biomedical Data Sciences, Leiden University Medical Centre, Leiden, the Netherlands., Bossios A; Karolinska Severe Asthma Centre, Department of Respiratory Medicine and Allergy, Karolinska University Hospital, Stockholm, Sweden.; Division for Lung and Airway Research, Institute for Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.; Lung Laboratory, Centre for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden., Ainsworth B; School of Psychology, Faculty of Environmental and Life Sciences, University of Southampton, Southampton, UK., Hyland M; School of Psychology, University of Plymouth, Plymouth, UK., Chaudhuri R; School of Infection and Immunity, University of Glasgow, Scotland., Matisa D; Riga East University Hospital, Latvia., Mihaltan F; Național Institute of Pneumology, Bucharest, Romania., Spanevello A; Department of Cardiopulmonary Rehabilitation, Istituti Clinici Scientifici Maugeri IRCCS, Tradate, Italy.; Department of Medicine and Surgery, University of Insubria, Varese, Italy., Heffler E; Personalized Medicine, Asthma and Allergy - IRCCS Humanitas Research Hospital, Rozzano, MI, Italy.; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, MI, Italy., Adcock I; National Heart & Lung Institute, Imperial College London, UK., Zappa M; Department of Cardiopulmonary Rehabilitation, Istituti Clinici Scientifici Maugeri IRCCS, Tradate, Italy., Canonica GW; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, MI, Italy.; Personalized Medicine, Asthma and Allergy - IRCCS Humanitas Research Hospital, Rozzano, MI, Italy., Brusselle G; Department of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium., Bourdin A; Department of Respiratory Diseases, Montpellier University Hospital, Arnaud de Villeneuve Hospital, Montpellier, France.; PhyMedExp (INSERM U 1046, CNRS UMR9214), Montpellier University, Montpellier, France., Maria Luigia Costanzo GA; Department of Medical Science and Public Health, University of Cagliari, Cagliari, Italy., Horvath I; National Koranyi Institute of Pulmonology, Budapest, Hungary., Lúðvíksdóttir D; Department of Respiratory Medicine, Landspitali University Hospital and University of Iceland, Iceland., Principe S; Amsterdam University Medical Centre, the Netherlands., Kopač P; University Clinic of Respiratory Diseases Golnik, Slovenia.; Faculty of Medicine, University of Ljubljana, Slovenia., Loureiro CC; Pneumology Unit, Hospitais da Universidade de Coimbra, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal., Siddiqui S; National Heart & Lung Institute, Imperial College London, UK., Egesten A; Department of Clinical Sciences Lund, Respiratory Medicine, Allergology, & Palliative Medicine, Lund University and Skåne University Hospital, Lund, Sweden., Kalinauskaite-Zukauske V; Department of Pulmonology, Lithuanian University of Health Sciences, Kaunas, Lithuania., Dimic-Janjic S; Faculty of Medicine, University of Belgrade, Belgrade, Serbia.; Clinic for Pulmonary Diseases, University Clinical Centre of Serbia, Belgrade, Serbia., Roberts G; School of Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, UK.; National Institute for Health Research (NIHR) Southampton Biomedical Research Centre at University Hospital Southampton NHS Foundation Trust, Southampton, UK.; The David Hide Asthma & Allergy Research Centre, St Mary's Hospital, Newport, Isle of Wight, UK., Hromis S; Institute for Pulmonary Diseases of Vojvodina, Sremska Kamenica, Serbia.; Faculty of Medicine, University in Novi Sad, Serbia., Milenkovic B; Clinic for Pulmonary Diseases, University Clinical Centre of Serbia, Belgrade, Serbia.; Faculty of Medicine, University of Belgrade, Belgrade, Serbia., Varkonyi-Sepp J; School of Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, UK.; National Institute for Health Research (NIHR) Southampton Biomedical Research Centre at University Hospital Southampton NHS Foundation Trust, Southampton, UK.; Clinical Health Psychology Department, Southern Health NHS Foundation Trust/University Hospital Southampton NHS Foundation Trust, Southampton, UK., Goksel O; Department of Pulmonary Diseases, Ege University Faculty of Medicine, İzmir, Türkiye., Pereira AM; MEDCIDS-Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine, University of Porto, Porto, Portugal.; PaCeIT - Patient Centred Innovation and Technologies, CINTESIS@RISE - Health Research Network, Faculty of Medicine, University of Porto, Porto, Portugal.; Allergy Unit, Instituto and Hospital CUF, Porto, Portugal., Djukanovic R; National Institute for Health Research (NIHR) Southampton Biomedical Research Centre at University Hospital Southampton NHS Foundation Trust, Southampton, UK.; School of Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, UK., Rizzi A; UOSD Allergologia e Immunologia Clinica. Dipartimento Scienze Mediche e Chirurgiche. Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy., Caminati M; Department of Medicine, University of Verona, Verona, Italy., Hou R; School of Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, UK., Štajduhar A; Clinic for pulmonary diseases Jordanovac, University Hospital Centre Zagreb, Croatia.; University of Zagreb School of Medicine, as an external collaborator., Paróczai D; Department of Pulmonology, University of Szeged, Hungary., Brussino L; Allergy and Immunology unit, Department of medical sciences, University of Turin, Italy., Heaney L; Wellcome-Wolfson Centre for Experimental Medicine, Queen's University Belfast, UK., Haitchi HM; School of Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, UK.; National Institute for Health Research (NIHR) Southampton Biomedical Research Centre at University Hospital Southampton NHS Foundation Trust, Southampton, UK., Bonini M; Department of Public Health and Infectious Diseases, Sapienza University of Rome, Italy.; National Heart & Lung Institute, Imperial College London, UK., Bieksiene K; Department of Pulmonology, Lithuanian University of Health Sciences, Kaunas, Lithuania., Damadoglu E; Department of Pulmonology, Division of Allergy and Clinical Immunology, Hacettepe University, School of Medicine, Ankara, Türkiye., Yasinska V; Karolinska Severe Asthma Centre, Department of Respiratory Medicine and Allergy, Karolinska University Hospital, Stockholm, Sweden.; Clinical Lung and Allergy Research, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden., Gemicioglu B; Department of Pulmonary Diseases, Istanbul University-Cerrahpaşa, Cerrahpaşa Faculty of Medicine, Istanbul, Türkiye.; Institute of Pulmonology and Tuberculosis, Istanbul University-Cerrahpaşa, Istanbul., Grle SP; Clinic for pulmonary diseases Jordanovac, University Hospital Centre Zagreb, Croatia.; School of Medicine, University of Zagreb, Zagreb, Croatia., Brinke AT; Department of Respiratory Medicine, Medical Centre Leeuwarden, Leeuwarden, the Netherlands., Csoma Z; National Koranyi Institute of Pulmonology, Budapest, Hungary., Kroica I; Riga East University Hospital, Latvia., Kuna P; Medical University of Lodz, Poland., Dahlen B; Clinical Lung and Allergy Research, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden.; Department of Respiratory Medicine, Karolinska University Hospital, Stockholm, Sweden., Porsbjerg C; Department of Respiratory and Infectious Diseases, Bispebjerg Hospital, Copenhagen, Denmark.; Institute of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark., Hodge H; European Lung Foundation, UK., Škrgat S; Department of Pulmonary Diseases and Allergy, University Medical Centre Ljubljana, Slovenia.; Faculty of Medicine, University of Ljubljana, Slovenia., Schleich F; Lab of Exercise Physiology, University of Liege, Belgium., Kurukulaaratchy RJ; School of Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, UK.; National Institute for Health Research (NIHR) Southampton Biomedical Research Centre at University Hospital Southampton NHS Foundation Trust, Southampton, UK.; The David Hide Asthma & Allergy Research Centre, St Mary's Hospital, Newport, Isle of Wight, UK.; Respiratory Medicine Department, University Hospital Southampton NHS Foundation Trust, Southampton, UK.
Source: The Lancet regional health. Europe [Lancet Reg Health Eur] 2026 Feb 05; Vol. 63, pp. 101600. Date of Electronic Publication: 2026 Feb 05 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: [Oxford] Country of Publication: England NLM ID: 101777707 Publication Model: eCollection Cited Medium: Internet ISSN: 2666-7762 (Electronic) Linking ISSN: 26667762 NLM ISO Abbreviation: Lancet Reg Health Eur Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2666-7762
DOI:10.1016/j.lanepe.2026.101600