Sex-specific differences in abscopal responses to combined radiotherapy and immune checkpoint inhibition-insights from a multicenter study.
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| Title: | Sex-specific differences in abscopal responses to combined radiotherapy and immune checkpoint inhibition-insights from a multicenter study. |
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| Authors: | Trommer M; Department of Radiation Oncology, Faculty of Medicine and University Hospital Bonn, Bonn, Germany., Rühle A; Department of Radiation Oncology, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Department of Radiation Oncology, University of Leipzig Medical Center, Leipzig, Germany., Ehret F; Department of Radiation Oncology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.; German Cancer Consortium (DKTK), partner site Berlin, a partnership between DKFZ and Charité - Universitätsmedizin, Berlin, Germany., Lamrani A; Department of Radiation Oncology, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany., Schmitter C; Department of Radiation Oncology, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.; Comprehensive Cancer Center Erlangen-Erlangen-Metropolregion Nürnberg (EMN), Erlangen, Germany., Kaufmann J; Department of Radiation Oncology, University Medical Center of the Johannes Gutenberg University, Mainz, Germany., Mäurer M; Department of Radiotherapy and Radiation Oncology, Jena University Hospital, Jena, Germany.; Clinician Scientist Program OrganAge, Jena University Hospital, Jena, Germany., Wurschi G; Department of Radiotherapy and Radiation Oncology, Jena University Hospital, Jena, Germany.; Clinician Scientist Program, Interdisciplinary Center for Clinical Research (IZKF), Jena University Hospital, Jena, Germany., Jiang P; Clinic for Radiation Oncology and Radiotherapy, Lüdenscheid Clinic, Lüdenscheid, Germany., Baehr A; Department of Radiation Oncology, University Medical Hospital, Hamburg-Eppendorf, Hamburg, Germany., Hardt A; Department of Radiotherapy and Radiation Oncology, Outpatient Center of the University Medical Hospital Hamburg-Eppendorf, Hamburg,, Germany., Bodensohn R; Department of Radiation Oncology, University Hospital, Ludwig-Maximilians-Universität (LMU) Munich, Munich, Germany.; Department of Radiation Oncology, University Hospital Tübingen, Tübingen, Germany., Käsmann L; Department of Radiation Oncology, University Hospital, Ludwig-Maximilians-Universität (LMU) Munich, Munich, Germany., Waltenberger M; Department of Radiation Oncology, Hospital of Bolzano (SABES-ASDAA), Bolzano-Bozen, Italy.; Teaching Hospital of Paracelsus Medical University Salzburg, Salzburg, Austria.; Department of Radiation Oncology, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany., Gkika E; Department of Radiation Oncology, Faculty of Medicine and University Hospital Bonn, Bonn, Germany., Scafa D; Department of Radiation Oncology, Faculty of Medicine and University Hospital Bonn, Bonn, Germany., Layer JP; Department of Radiation Oncology, Faculty of Medicine and University Hospital Bonn, Bonn, Germany.; Institute of Experimental Oncology, University Hospital Bonn, Bonn, Germany., Troost EGC; OncoRay - National Center for Radiation Research in Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, and Helmholtz-Zentrum Dresden- Rossendorf, Institute of Radiooncology - OncoRay Helmholtz- Zentrum Dresden-Rossendorf, Dresden, Germany.; National Center for Tumor Diseases (NCT/UCC), Dresden, Germany.; National Center for Tumor Diseases (NCT/UCC), Dresden, Germany; German Cancer Research Center (DKFZ), Heidelberg, Germany, Medizinische Fakultät and University, Hospital Carl Gustav Carus Technische Universität Dresden, Germany; Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, Germany., Elkhamisy SA; National Center for Tumor Diseases (NCT/UCC), Dresden, Germany; German Cancer Research Center (DKFZ), Heidelberg, Germany, Medizinische Fakultät and University, Hospital Carl Gustav Carus Technische Universität Dresden, Germany; Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, Germany., Jazmati D; University Hospital Dusseldorf, Medical Faculty, Heinrich-Heine-University Dusseldorf, Department of Radiation Oncology, Dusseldorf, Germany., Popp I; Department of Radiation Oncology, University of Leipzig Medical Center, Leipzig, Germany., Neppl S; Department of Radiation Oncology, Cyberknife and Radiotherapy, Faculty of Medicine and University Hospital Cologne, Cologne, Germany., Hagemeier A; Institute of Medical Statistics and Computational Biology, Medical Faculty and University Hospital, University of Cologne, Cologne, Germany., Besserer A; Department of Radiation Oncology, Ernst von Bergmann Hospital Potsdam, Potsdam, Germany., Ferdinandus S; Department of Radiation Oncology, Cyberknife and Radiotherapy, Faculty of Medicine and University Hospital Cologne, Cologne, Germany. |
| Source: | Frontiers in immunology [Front Immunol] 2026 Feb 02; Vol. 16, pp. 1699362. Date of Electronic Publication: 2026 Feb 02 (Print Publication: 2025). |
| Publication Type: | Journal Article; Multicenter Study; Observational Study |
| Journal Info: | Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1664-3224 |
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| DOI: | 10.3389/fimmu.2025.1699362 |
