Baloxavir alleviates severe disease and viremia in ferrets infected with avian- or bovine-origin influenza A(H5N1) virus.

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Title: Baloxavir alleviates severe disease and viremia in ferrets infected with avian- or bovine-origin influenza A(H5N1) virus.
Authors: Jones JC; Department of Host-Microbe Interactions, St. Jude Children's Research Hospital, Memphis, TN 38120, USA., Andreev K; Department of Host-Microbe Interactions, St. Jude Children's Research Hospital, Memphis, TN 38120, USA., Sheth V; Center of Excellence for Data Driven Discovery, Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN 38120, USA., Rowbotham K; Center of Excellence for Data Driven Discovery, Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN 38120, USA., Vogel P; Department of Comparative Pathology, St. Jude Children's Research Hospital, Memphis, TN 38120, USA., Patton CJ; Department of Host-Microbe Interactions, St. Jude Children's Research Hospital, Memphis, TN 38120, USA., Seiler P; Department of Host-Microbe Interactions, St. Jude Children's Research Hospital, Memphis, TN 38120, USA., Franks J; Department of Host-Microbe Interactions, St. Jude Children's Research Hospital, Memphis, TN 38120, USA., Kandeil A; Department of Host-Microbe Interactions, St. Jude Children's Research Hospital, Memphis, TN 38120, USA.; Center of Scientific Excellence for Influenza Viruses, National Research Centre, Giza, 12622, Egypt., Miller L; Department of Host-Microbe Interactions, St. Jude Children's Research Hospital, Memphis, TN 38120, USA., Babu MM; Center of Excellence for Data Driven Discovery, Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN 38120, USA., Webby RJ; Department of Host-Microbe Interactions, St. Jude Children's Research Hospital, Memphis, TN 38120, USA., Govorkova EA; Department of Host-Microbe Interactions, St. Jude Children's Research Hospital, Memphis, TN 38120, USA.
Source: Science translational medicine [Sci Transl Med] 2026 Feb 18; Vol. 18 (837), pp. eadt3889. Date of Electronic Publication: 2026 Feb 18.
Publication Type: Journal Article
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1946-6242
DOI:10.1126/scitranslmed.adt3889