The integrated stress response promotes immune evasion through lipocalin 2.

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Title: The integrated stress response promotes immune evasion through lipocalin 2.
Authors: Bossowski JP; Department of Pathology, New York University Grossman School of Medicine, New York, NY, USA., Pillai R; Department of Pathology, New York University Grossman School of Medicine, New York, NY, USA.; Division of Pulmonary and Critical Care Medicine, Department of Medicine, VA New York Harbor Healthcare System, New York, NY, USA.; Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, New York University Grossman School of Medicine, New York, NY, USA., Kilian J; Laura and Isaac Perlmutter Cancer Center, New York University Langone Health, New York, NY, USA.; Vilcek Institute of Graduate Biomedical Sciences, New York University Grossman School of Medicine, New York, NY, USA., Wong Lau A; Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA, USA.; Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA, USA., Nakamura M; Department of Pathology, New York University Grossman School of Medicine, New York, NY, USA.; Vilcek Institute of Graduate Biomedical Sciences, New York University Grossman School of Medicine, New York, NY, USA., Rashidfarrokhi A; Department of Pathology, New York University Grossman School of Medicine, New York, NY, USA.; Laura and Isaac Perlmutter Cancer Center, New York University Langone Health, New York, NY, USA., Hao Y; Department of Pathology, New York University Grossman School of Medicine, New York, NY, USA.; Applied Bioinformatics Laboratories, New York University Langone Health, New York, NY, USA., Li R; Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA, USA.; Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA, USA., Wu K; Department of Pathology, New York University Grossman School of Medicine, New York, NY, USA.; Vilcek Institute of Graduate Biomedical Sciences, New York University Grossman School of Medicine, New York, NY, USA., Hattori T; Laura and Isaac Perlmutter Cancer Center, New York University Langone Health, New York, NY, USA.; Department of Biochemistry and Molecular Pharmacology, New York University Grossman School of Medicine, New York, NY, USA., Glasser E; Laura and Isaac Perlmutter Cancer Center, New York University Langone Health, New York, NY, USA., Koide A; Laura and Isaac Perlmutter Cancer Center, New York University Langone Health, New York, NY, USA.; Department of Medicine, New York University Grossman School of Medicine, New York, NY, USA., Wang L; Department of Biochemistry and Molecular Pharmacology, New York University Grossman School of Medicine, New York, NY, USA.; Moores Cancer Center, University of California, San Diego, La Jolla, CA, USA., Moreira AL; Department of Pathology, New York University Grossman School of Medicine, New York, NY, USA.; Center for Biospecimen Research and Development, New York University, New York, NY, USA., Hajdu C; Department of Pathology, New York University Grossman School of Medicine, New York, NY, USA., Rajalingam S; Department of Pathology, New York University Grossman School of Medicine, New York, NY, USA., LeBoeuf SE; Department of Pathology, New York University Grossman School of Medicine, New York, NY, USA., Le H; Department of Pathology, New York University Grossman School of Medicine, New York, NY, USA.; Division of Precision Medicine, Department of Medicine, New York University Grossman School of Medicine, New York, NY, USA., Lee S; Lunit, Seoul, Republic of Korea., Oh JW; Lunit, Seoul, Republic of Korea., Joe C; Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.; Department of Health Sciences and Technology, Samsung Advanced Institute of Health Sciences and Technology, Sungkyunkwan University, Seoul, Republic of Korea., Kim H; Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea., Ock CY; Lunit, Seoul, Republic of Korea., Lee SH; Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.; Department of Health Sciences and Technology, Samsung Advanced Institute of Health Sciences and Technology, Sungkyunkwan University, Seoul, Republic of Korea., Wang H; Department of Pathology, New York University Grossman School of Medicine, New York, NY, USA., Patel AAH; Sahlgrenska Center for Cancer Research, Department of Surgery, Institute of Clinical Sciences, University of Gothenburg, Gothenburg, Sweden.; Wallenberg Centre for Molecular and Translational Medicine, University of Gothenburg, Gothenburg, Sweden., Sayin VI; Sahlgrenska Center for Cancer Research, Department of Surgery, Institute of Clinical Sciences, University of Gothenburg, Gothenburg, Sweden.; Wallenberg Centre for Molecular and Translational Medicine, University of Gothenburg, Gothenburg, Sweden., Tsirigos A; Department of Pathology, New York University Grossman School of Medicine, New York, NY, USA.; Applied Bioinformatics Laboratories, New York University Langone Health, New York, NY, USA., Wong KK; Department of Pathology, New York University Grossman School of Medicine, New York, NY, USA.; Division of Hematology and Oncology, Department of Medicine, New York University Grossman School of Medicine, New York, NY, USA., Koralov SB; Department of Pathology, New York University Grossman School of Medicine, New York, NY, USA.; Laura and Isaac Perlmutter Cancer Center, New York University Langone Health, New York, NY, USA., Pende M; Institut Necker Enfants Malades (INEM), Université Paris Cité, CNRS, Inserm, Paris, France., Sánchez-Rivera FJ; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA.; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA., Simeone DM; Moores Cancer Center, University of California, San Diego, La Jolla, CA, USA., Zervantonakis IK; Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA, USA.; Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA, USA., Koide S; Laura and Isaac Perlmutter Cancer Center, New York University Langone Health, New York, NY, USA. Shohei.Koide@nyulangone.org.; Department of Biochemistry and Molecular Pharmacology, New York University Grossman School of Medicine, New York, NY, USA. Shohei.Koide@nyulangone.org., Papagiannakopoulos T; Department of Pathology, New York University Grossman School of Medicine, New York, NY, USA. Thales.Papagiannakopoulos@nyulangone.org.; Laura and Isaac Perlmutter Cancer Center, New York University Langone Health, New York, NY, USA. Thales.Papagiannakopoulos@nyulangone.org.
Source: Nature [Nature] 2026 Apr; Vol. 652 (8112), pp. 1329-1338. Date of Electronic Publication: 2026 Feb 18.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1476-4687
DOI:10.1038/s41586-026-10143-0