Treatment for Brain Metastases With Stereotactic Radiation vs Hippocampal-Avoidance Whole Brain Radiation: A Randomized Clinical Trial.
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| Title: | Treatment for Brain Metastases With Stereotactic Radiation vs Hippocampal-Avoidance Whole Brain Radiation: A Randomized Clinical Trial. |
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| Authors: | Aizer AA; Department of Radiation Oncology, Brigham and Women's Hospital, Dana-Farber Cancer Institute, Boston, Massachusetts., Shin KY; Department of Data Science, Dana-Farber Cancer Institute, Boston, Massachusetts., Catalano PJ; Department of Data Science, Dana-Farber Cancer Institute, Boston, Massachusetts.; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, Massachusetts., Ricca I; Department of Radiation Oncology, Brigham and Women's Hospital, Dana-Farber Cancer Institute, Boston, Massachusetts., Johnson M; Department of Radiation Oncology, Brigham and Women's Hospital, Dana-Farber Cancer Institute, Boston, Massachusetts., Benham G; Department of Radiation Oncology, Brigham and Women's Hospital, Dana-Farber Cancer Institute, Boston, Massachusetts., Roper K; Department of Radiation Oncology, Milford Regional Medical Center, Milford, Massachusetts.; Department of Radiation Oncology, South Shore Health, Weymouth, Massachusetts., Spicer B; Department of Radiation Oncology, Brigham and Women's Hospital, Dana-Farber Cancer Institute, Boston, Massachusetts., Mann E; Department of Radiation Oncology, Brigham and Women's Hospital, Dana-Farber Cancer Institute, Boston, Massachusetts., Nosker J; Department of Neurology, Brigham and Women's Hospital, Boston, Massachusetts., Parsons MW; Department of Psychiatry, Massachusetts General Hospital, Boston., Mendu ML; Population Health Services Organization, Mass General Brigham, Boston, Massachusetts., Hepel J; Department of Radiation Oncology, Rhode Island Hospital/Brown University, Providence., Chipidza F; Department of Radiation Oncology, Milford Regional Medical Center, Milford, Massachusetts.; Department of Radiation Oncology, South Shore Health, Weymouth, Massachusetts., Krishnan M; Department of Radiation Oncology, Milford Regional Medical Center, Milford, Massachusetts.; Department of Radiation Oncology, South Shore Health, Weymouth, Massachusetts., Shi DD; Department of Radiation Oncology, Brigham and Women's Hospital, Dana-Farber Cancer Institute, Boston, Massachusetts., Lamba N; Department of Radiation Oncology, Brigham and Women's Hospital, Dana-Farber Cancer Institute, Boston, Massachusetts., Pashtan I; Department of Radiation Oncology, Milford Regional Medical Center, Milford, Massachusetts.; Department of Radiation Oncology, South Shore Health, Weymouth, Massachusetts., Peng L; Department of Radiation Oncology, Milford Regional Medical Center, Milford, Massachusetts.; Department of Radiation Oncology, South Shore Health, Weymouth, Massachusetts., Alexander B; Valo Health, Lexington, Massachusetts., Brown PD; Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota., Wen PY; Center for Neuro-Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Haas-Kogan DA; Department of Radiation Oncology, Brigham and Women's Hospital, Dana-Farber Cancer Institute, Boston, Massachusetts., Rahman R; Department of Radiation Oncology, Brigham and Women's Hospital, Dana-Farber Cancer Institute, Boston, Massachusetts., Tanguturi S; Department of Radiation Oncology, Brigham and Women's Hospital, Dana-Farber Cancer Institute, Boston, Massachusetts. |
| Source: | JAMA [JAMA] 2026 Apr 07; Vol. 335 (13), pp. 1127-1136. |
| Publication Type: | Clinical Trial, Phase III; Comparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial |
| Journal Info: | Publisher: American Medical Association Country of Publication: United States NLM ID: 7501160 Publication Model: Print Cited Medium: Internet ISSN: 1538-3598 (Electronic) Linking ISSN: 00987484 NLM ISO Abbreviation: JAMA Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1538-3598 |
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| DOI: | 10.1001/jama.2026.0076 |
