A subunit-selective negative allosteric modulator of GluN1/GluN3A glycine-activated receptor.

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Title: A subunit-selective negative allosteric modulator of GluN1/GluN3A glycine-activated receptor.
Authors: Jacobs L; Department of Chemistry, Emory University, Atlanta, Georgia., Nguyen TT; Department of Pharmacology and Chemical Biology, Emory University School of Medicine, Atlanta Georgia., McCallum A; Department of Chemistry, Emory University, Atlanta, Georgia., Epplin MP; Department of Chemistry, Emory University, Atlanta, Georgia., Perszyk RE; Department of Pharmacology and Chemical Biology, Emory University School of Medicine, Atlanta Georgia., Myers SJ; Department of Pharmacology and Chemical Biology, Emory University School of Medicine, Atlanta Georgia., Liu K; Department of Chemistry, Emory University, Atlanta, Georgia., Yang Y; Department of Chemistry, Emory University, Atlanta, Georgia., Van der Westhuyzen AE; Department of Chemistry, Emory University, Atlanta, Georgia., Nocilla KA; Department of Pharmacology and Chemical Biology, Emory University School of Medicine, Atlanta Georgia., Allen J; Department of Pharmacology and Chemical Biology, Emory University School of Medicine, Atlanta Georgia., Ullman EZ; Department of Pharmacology and Chemical Biology, Emory University School of Medicine, Atlanta Georgia., Liu D; Department of Pharmacology and Chemical Biology, Emory University School of Medicine, Atlanta Georgia., Du Y; Department of Cell Biology, Emory University School of Medicine, Atlanta, Georgia., Yuan H; Department of Pharmacology and Chemical Biology, Emory University School of Medicine, Atlanta Georgia., Liotta DC; Department of Chemistry, Emory University, Atlanta, Georgia; Department of Pharmacology and Chemical Biology, Emory University School of Medicine, Atlanta Georgia. Electronic address: dliotta@emory.edu., Traynelis SF; Department of Pharmacology and Chemical Biology, Emory University School of Medicine, Atlanta Georgia. Electronic address: strayne@emory.edu.
Source: Molecular pharmacology [Mol Pharmacol] 2026 Mar; Vol. 108 (3), pp. 100104. Date of Electronic Publication: 2026 Jan 29.
Publication Type: Journal Article
Journal Info: Publisher: American Society for Pharmacology and Experimental Therapeutics Country of Publication: Netherlands NLM ID: 0035623 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-0111 (Electronic) Linking ISSN: 0026895X NLM ISO Abbreviation: Mol Pharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1521-0111
DOI:10.1016/j.molpha.2026.100104