Multi-modal integrated intervention combining exercise, anti-inflammatory, and dietary advice (MMIEAD) for adults with kidney cachexia: protocol for a mixed-methods feasibility cluster randomised controlled trial and process evaluation.

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Title: Multi-modal integrated intervention combining exercise, anti-inflammatory, and dietary advice (MMIEAD) for adults with kidney cachexia: protocol for a mixed-methods feasibility cluster randomised controlled trial and process evaluation.
Authors: Reid J; School of Nursing and Midwifery, Queen's University Belfast, Belfast, UK. j.reid@qub.ac.uk., Blair C; School of Nursing and Midwifery, Queen's University Belfast, Belfast, UK., Slee A; Division of Medicine, Faculty of Medical Sciences, University College London, London, UK., McKeaveney C; School of Nursing and Midwifery, Queen's University Belfast, Belfast, UK., Maxwell AP; Centre for Public Health, Queen's University Belfast, Belfast, UK., Adell V; South Eastern Health and Social Care Trust, Renal Unit Ulster Hospital, Upper Newtownards Rd., Belfast, UK., Carson M; Renal Unit, Antrim Area Hospital, Northern Health & Social Care Trust, Antrim, UK., Awan F; Renal Patient Led Advisory Network (RPLAN), Lancashire, UK., Brown M; School of Sport and Exercise Science, Ulster University, Belfast, UK., Davenport A; UCL Department of Renal Medicine, Royal Free Hospital, University College London Medical School, London, UK., Fogarty D; Regional Nephrology Unit, Belfast City Hospital, Belfast Health & Social Care Trust, Belfast, UK., Fouque D; Division of Nephrology, Dialysis, and Nutrition, Hôpital Lyon Sud and University of Lyon, Lyon, France., Gooding O; Renal Unit, Antrim Area Hospital, Northern Health & Social Care Trust, Antrim, UK., McKinley T; Southern Health and Social Care Trust, Renal Unit, Daisy Hill Hospital, Newry, UK., Hagan S; South Eastern Health and Social Care Trust, Renal Unit Ulster Hospital, Upper Newtownards Rd., Belfast, UK., Hutchinson C; Southern Health and Social Care Trust, Renal Unit, Daisy Hill Hospital, Newry, UK., Kalantar-Zadeh K; Irvine Division of Nephrology, Hypertension, and Kidney Transplantation, University of California, Berkeley, USA., Magee K; Regional Nephrology Unit, Belfast City Hospital, Belfast Health & Social Care Trust, Belfast, UK., Mullan R; Renal Unit, Antrim Area Hospital, Northern Health & Social Care Trust, Antrim, UK., Morgan N; Southern Health and Social Care Trust, Renal Unit, Daisy Hill Hospital, Newry, UK., Noble H; School of Nursing and Midwifery, Queen's University Belfast, Belfast, UK., Porter S; Department of Social Sciences and Social Work, Bournemouth University, Poole, UK., Seres DS; Institute of Human Nutrition and Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA., Shields J; Regional Nephrology Unit, Belfast City Hospital, Belfast Health & Social Care Trust, Belfast, UK., Swaine I; School of Human Sciences, University of Greenwich, London, UK., Witham M; AGE Research Group, NIHR Newcastle Biomedical Research Centre, Newcastle University, Newcastle upon Tyne, UK.
Corporate Authors: NICRN Clinical Research Team
Source: Pilot and feasibility studies [Pilot Feasibility Stud] 2026 Feb 19; Vol. 12 (1). Date of Electronic Publication: 2026 Feb 19.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101676536 Publication Model: Electronic Cited Medium: Print ISSN: 2055-5784 (Print) Linking ISSN: 20555784 NLM ISO Abbreviation: Pilot Feasibility Stud Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2055-5784
DOI:10.1186/s40814-026-01784-z