Angiographic Burden of Coronary Atherosclerosis Partially Mediates the Association Between ASCVD Risk Factors and Outcomes.

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Title: Angiographic Burden of Coronary Atherosclerosis Partially Mediates the Association Between ASCVD Risk Factors and Outcomes.
Authors: Tsao NL; Department of Surgery (N.L.T., S.A.A., G.E.S., R.J., S.M.D.), University of Pennsylvania Perelman School of Medicine, Philadelphia., Abramowitz SA; Department of Surgery (N.L.T., S.A.A., G.E.S., R.J., S.M.D.), University of Pennsylvania Perelman School of Medicine, Philadelphia., Shakt GE; Department of Surgery (N.L.T., S.A.A., G.E.S., R.J., S.M.D.), University of Pennsylvania Perelman School of Medicine, Philadelphia., Judy R; Department of Surgery (N.L.T., S.A.A., G.E.S., R.J., S.M.D.), University of Pennsylvania Perelman School of Medicine, Philadelphia., Hilliard AT; VA Palo Alto Health Care System (A.T.H., T.L.A., S.L.C., C.T.).; Division of Cardiovascular Medicine, Department of Medicine (A.T.H., T.L.A., S.L.C., C.T.), Stanford University School of Medicine, CA., Damrauer SM; Department of Surgery (N.L.T., S.A.A., G.E.S., R.J., S.M.D.), University of Pennsylvania Perelman School of Medicine, Philadelphia., Assimes TL; VA Palo Alto Health Care System (A.T.H., T.L.A., S.L.C., C.T.).; Division of Cardiovascular Medicine, Department of Medicine (A.T.H., T.L.A., S.L.C., C.T.), Stanford University School of Medicine, CA.; Cardiovascular Institute (T.L.A.), Stanford University School of Medicine, CA.; Department of Epidemiology and Population Health (T.L.A.), Stanford University School of Medicine, CA., Clarke SL; VA Palo Alto Health Care System (A.T.H., T.L.A., S.L.C., C.T.).; Division of Cardiovascular Medicine, Department of Medicine (A.T.H., T.L.A., S.L.C., C.T.), Stanford University School of Medicine, CA., Tcheandjieu C; VA Palo Alto Health Care System (A.T.H., T.L.A., S.L.C., C.T.).; Division of Cardiovascular Medicine, Department of Medicine (A.T.H., T.L.A., S.L.C., C.T.), Stanford University School of Medicine, CA.; Corporal Michael J. Crescenz, VA Medical Center, Philadelphia, PA (S.M.D., M.G.L.). Gladstone Institute of Data Science & Biotechnology, Gladstone Institutes (C.T.).; Department of Epidemiology and Biostatistics, University of California San Francisco (C.T.)., Levin MG; Division of Cardiovascular Medicine, Department of Medicine (M.G.L.), University of Pennsylvania Perelman School of Medicine, Philadelphia.
Corporate Authors: Penn Medicine Biobank
Source: Circulation. Genomic and precision medicine [Circ Genom Precis Med] 2026 Apr; Vol. 19 (2), pp. e005266. Date of Electronic Publication: 2026 Feb 20.
Publication Type: Journal Article
Journal Info: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 101714113 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2574-8300 (Electronic) Linking ISSN: 25748300 NLM ISO Abbreviation: Circ Genom Precis Med Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2574-8300
DOI:10.1161/CIRCGEN.125.005266