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A Meier-Gorlin syndrome mutation impairs the loading of the MCM2-7 complex during DNA replication initiation.

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Bibliographic Details
Title: A Meier-Gorlin syndrome mutation impairs the loading of the MCM2-7 complex during DNA replication initiation.
Authors: Liu Y; School of Life Sciences, Fudan University, Shanghai 200433, China.; School of Life Sciences, Westlake University, Hangzhou, Zhejiang 310030, China.; Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, Zhejiang 310024, China.; New Cornerstone Science Laboratory, School of Life Sciences, Westlake University, Hangzhou, Zhejiang 310030, China., Yang M; School of Life Sciences, Westlake University, Hangzhou, Zhejiang 310030, China.; Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, Zhejiang 310024, China.; New Cornerstone Science Laboratory, School of Life Sciences, Westlake University, Hangzhou, Zhejiang 310030, China.; College of Life Sciences, Zhejiang University, Hangzhou, Zhejiang 310058, China., Lu P; School of Life Sciences, Westlake University, Hangzhou, Zhejiang 310030, China.; Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, Zhejiang 310024, China.; New Cornerstone Science Laboratory, School of Life Sciences, Westlake University, Hangzhou, Zhejiang 310030, China.; College of Life Sciences, Zhejiang University, Hangzhou, Zhejiang 310058, China., Gao H; School of Life Sciences, Westlake University, Hangzhou, Zhejiang 310030, China.; Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, Zhejiang 310024, China.; New Cornerstone Science Laboratory, School of Life Sciences, Westlake University, Hangzhou, Zhejiang 310030, China.; Zhejiang Key Laboratory of Structural Biology, School of Life Sciences, Westlake University, Hangzhou, Zhejiang 310024, China., He M; School of Life Sciences, Westlake University, Hangzhou, Zhejiang 310030, China.; Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, Zhejiang 310024, China.; New Cornerstone Science Laboratory, School of Life Sciences, Westlake University, Hangzhou, Zhejiang 310030, China., Wang Y; School of Life Sciences, Westlake University, Hangzhou, Zhejiang 310030, China.; Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, Zhejiang 310024, China.; New Cornerstone Science Laboratory, School of Life Sciences, Westlake University, Hangzhou, Zhejiang 310030, China., Qi A; School of Life Sciences, Westlake University, Hangzhou, Zhejiang 310030, China.; Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, Zhejiang 310024, China.; New Cornerstone Science Laboratory, School of Life Sciences, Westlake University, Hangzhou, Zhejiang 310030, China., Cao T; School of Life Sciences, Westlake University, Hangzhou, Zhejiang 310030, China.; Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, Zhejiang 310024, China.; New Cornerstone Science Laboratory, School of Life Sciences, Westlake University, Hangzhou, Zhejiang 310030, China., Zhang Q; School of Life Sciences, Westlake University, Hangzhou, Zhejiang 310030, China.; Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, Zhejiang 310024, China.; New Cornerstone Science Laboratory, School of Life Sciences, Westlake University, Hangzhou, Zhejiang 310030, China., Qi S; School of Life Sciences, Westlake University, Hangzhou, Zhejiang 310030, China.; Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, Zhejiang 310024, China.; New Cornerstone Science Laboratory, School of Life Sciences, Westlake University, Hangzhou, Zhejiang 310030, China., Shi Y; School of Life Sciences, Westlake University, Hangzhou, Zhejiang 310030, China.; Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, Zhejiang 310024, China.; Zhejiang Key Laboratory of Structural Biology, School of Life Sciences, Westlake University, Hangzhou, Zhejiang 310024, China., Yu H; School of Life Sciences, Westlake University, Hangzhou, Zhejiang 310030, China.; Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, Zhejiang 310024, China.; New Cornerstone Science Laboratory, School of Life Sciences, Westlake University, Hangzhou, Zhejiang 310030, China.
Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2026 Feb 24; Vol. 123 (8), pp. e2526022123. Date of Electronic Publication: 2026 Feb 20.
Publication Type: Journal Article
Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1091-6490
DOI:10.1073/pnas.2526022123