In situ structures of the portal-neck-tail complex of bacteriophage T4 inform a viral genome positioning mechanism.

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Title: In situ structures of the portal-neck-tail complex of bacteriophage T4 inform a viral genome positioning mechanism.
Authors: Fokine A; Department of Biological Sciences, Purdue University, West Lafayette, IN, USA. afokine@purdue.edu.; Bacteriophage Medical Research Center, Department of Biology, The Catholic University of America, Washington, DC, USA. afokine@purdue.edu., Zhu J; Bacteriophage Medical Research Center, Department of Biology, The Catholic University of America, Washington, DC, USA., Klose T; Department of Biological Sciences, Purdue University, West Lafayette, IN, USA., Vago F; Department of Biological Sciences, Purdue University, West Lafayette, IN, USA., Arnaud CA; Department of Biological Sciences, Purdue University, West Lafayette, IN, USA., Wang Z; Department of Biological Sciences, Purdue University, West Lafayette, IN, USA., Khare B; Department of Biological Sciences, Purdue University, West Lafayette, IN, USA., Rossmann MG; Department of Biological Sciences, Purdue University, West Lafayette, IN, USA., Chen Z; Shanghai Fifth People's Hospital and Institutes of Biomedical Sciences, Fudan University, Shanghai, China., Sun L; Shanghai Fifth People's Hospital and Institutes of Biomedical Sciences, Fudan University, Shanghai, China., Fang Q; School of Public Health (Shenzhen), Sun Yat-sen University, Shenzhen, Guangdong, China., Kuhn RJ; Department of Biological Sciences, Purdue University, West Lafayette, IN, USA., Rao VB; Bacteriophage Medical Research Center, Department of Biology, The Catholic University of America, Washington, DC, USA. rao@cua.edu.
Source: Nature communications [Nat Commun] 2026 Feb 20; Vol. 17 (1). Date of Electronic Publication: 2026 Feb 20.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-026-69106-8