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A scalable microbead-based cell culture platform presenting curvature cues for the enrichment of cancer stem cell-like phenotypes beyond 3D spheroid models.

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Title: A scalable microbead-based cell culture platform presenting curvature cues for the enrichment of cancer stem cell-like phenotypes beyond 3D spheroid models.
Authors: Yeun J; Department of Chemical and Biomolecular Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, 34141, Republic of Korea., Kim J; Department of Mechanical and Biomedical Engineering, Ewha Womans University, Seoul, 03760, Republic of Korea; Graduate Program in System Health Science and Engineering, Ewha Womans University, Seoul, 03760, Republic of Korea., Kim M; Department of Chemical and Biomolecular Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, 34141, Republic of Korea., Park S; Department of Chemical and Biomolecular Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, 34141, Republic of Korea., Yoon SH; Department of Chemical and Biomolecular Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, 34141, Republic of Korea., Sun SY; Department of Chemical and Biomolecular Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, 34141, Republic of Korea., Jeong B; Department of Chemical and Biomolecular Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, 34141, Republic of Korea., Im SG; Department of Chemical and Biomolecular Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, 34141, Republic of Korea; Graduate School of Stem Cell & Regenerative Biology, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, 34141, Republic of Korea. Electronic address: sgim@kaist.ac.kr., Baek J; Department of Mechanical and Biomedical Engineering, Ewha Womans University, Seoul, 03760, Republic of Korea; Graduate Program in System Health Science and Engineering, Ewha Womans University, Seoul, 03760, Republic of Korea. Electronic address: jieungbaek@ewha.ac.kr.
Source: Biomaterials advances [Biomater Adv] 2026 Jun; Vol. 183, pp. 214764. Date of Electronic Publication: 2026 Feb 10.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 9918383886206676 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2772-9508 (Electronic) Linking ISSN: 27729508 NLM ISO Abbreviation: Biomater Adv Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2772-9508
DOI:10.1016/j.bioadv.2026.214764