Xpert MTB/RIF assay as an initial diagnostic test in pulmonary tuberculosis: a multicenter prospective randomized pragmatic trial.

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Title: Xpert MTB/RIF assay as an initial diagnostic test in pulmonary tuberculosis: a multicenter prospective randomized pragmatic trial.
Authors: Huang WC; Department of Post-Baccalaureate Medicine, College of Medicine, National Chung Hsing University, Taichung, 402, Taiwan.; Division of Pulmonary Immunology & Infectious Diseases, Department of Chest Medicine, Taichung Veterans General Hospital, Taichung, 407, Taiwan.; School of Medicine, Chung Shan Medical University, Taichung, 402, Taiwan., Huang YW; Division of Chest Medicine, Department of Internal Medicine, Changhua Hospital, Ministry of Health and Welfare, Changhua, 513, Taiwan.; Institute of Medicine, Chung Shan Medical University, Taichung, 402, Taiwan., Lin CB; Division of Chest Medicine, Department of Internal Medicine, Hualien Tzu Chi Hospital, Hualien, 970, Taiwan.; School of Medicine, Tzu Chi University, Hualien, 970, Taiwan., Chien ST; Chest Hospital, Ministry of Health and Welfare, Tainan, 701, Taiwan., Lee CH; Division of Pulmonary Medicine, Department of Internal Medicine, Wan Fang Hospital, Taipei Medical University, 111 Hsin-Long Road, Section 3, Taipei, 116, Taiwan.; Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 110, Taiwan., Yu MC; Division of Pulmonary Medicine, Department of Internal Medicine, Wan Fang Hospital, Taipei Medical University, 111 Hsin-Long Road, Section 3, Taipei, 116, Taiwan.; School of Respiratory Therapy, College of Medicine, Taipei Medical University, Taipei, 110, Taiwan., Lee JJ; Division of Chest Medicine, Department of Internal Medicine, Hualien Tzu Chi Hospital, Hualien, 970, Taiwan., Chiang CY; Division of Pulmonary Medicine, Department of Internal Medicine, Wan Fang Hospital, Taipei Medical University, 111 Hsin-Long Road, Section 3, Taipei, 116, Taiwan. cychiang@theunion.org.; Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 110, Taiwan. cychiang@theunion.org.
Source: Scientific reports [Sci Rep] 2026 Feb 21; Vol. 16 (1). Date of Electronic Publication: 2026 Feb 21.
Publication Type: Journal Article; Randomized Controlled Trial; Multicenter Study; Pragmatic Clinical Trial
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2045-2322
DOI:10.1038/s41598-026-39022-4