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Xpert MTB/RIF assay as an initial diagnostic test in pulmonary tuberculosis: a multicenter prospective randomized pragmatic trial.

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Title: Xpert MTB/RIF assay as an initial diagnostic test in pulmonary tuberculosis: a multicenter prospective randomized pragmatic trial.
Authors: Huang WC; Department of Post-Baccalaureate Medicine, College of Medicine, National Chung Hsing University, Taichung, 402, Taiwan.; Division of Pulmonary Immunology & Infectious Diseases, Department of Chest Medicine, Taichung Veterans General Hospital, Taichung, 407, Taiwan.; School of Medicine, Chung Shan Medical University, Taichung, 402, Taiwan., Huang YW; Division of Chest Medicine, Department of Internal Medicine, Changhua Hospital, Ministry of Health and Welfare, Changhua, 513, Taiwan.; Institute of Medicine, Chung Shan Medical University, Taichung, 402, Taiwan., Lin CB; Division of Chest Medicine, Department of Internal Medicine, Hualien Tzu Chi Hospital, Hualien, 970, Taiwan.; School of Medicine, Tzu Chi University, Hualien, 970, Taiwan., Chien ST; Chest Hospital, Ministry of Health and Welfare, Tainan, 701, Taiwan., Lee CH; Division of Pulmonary Medicine, Department of Internal Medicine, Wan Fang Hospital, Taipei Medical University, 111 Hsin-Long Road, Section 3, Taipei, 116, Taiwan.; Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 110, Taiwan., Yu MC; Division of Pulmonary Medicine, Department of Internal Medicine, Wan Fang Hospital, Taipei Medical University, 111 Hsin-Long Road, Section 3, Taipei, 116, Taiwan.; School of Respiratory Therapy, College of Medicine, Taipei Medical University, Taipei, 110, Taiwan., Lee JJ; Division of Chest Medicine, Department of Internal Medicine, Hualien Tzu Chi Hospital, Hualien, 970, Taiwan., Chiang CY; Division of Pulmonary Medicine, Department of Internal Medicine, Wan Fang Hospital, Taipei Medical University, 111 Hsin-Long Road, Section 3, Taipei, 116, Taiwan. cychiang@theunion.org.; Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 110, Taiwan. cychiang@theunion.org.
Source: Scientific reports [Sci Rep] 2026 Feb 21; Vol. 16 (1). Date of Electronic Publication: 2026 Feb 21.
Publication Type: Journal Article; Randomized Controlled Trial; Multicenter Study; Pragmatic Clinical Trial
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Xpert MTB/RIF assay as an initial diagnostic test in pulmonary tuberculosis: a multicenter prospective randomized pragmatic trial.
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  Data: <searchLink fieldCode="AU" term="%22Huang+WC%22">Huang WC</searchLink>; Department of Post-Baccalaureate Medicine, College of Medicine, National Chung Hsing University, Taichung, 402, Taiwan.; Division of Pulmonary Immunology & Infectious Diseases, Department of Chest Medicine, Taichung Veterans General Hospital, Taichung, 407, Taiwan.; School of Medicine, Chung Shan Medical University, Taichung, 402, Taiwan.<br /><searchLink fieldCode="AU" term="%22Huang+YW%22">Huang YW</searchLink>; Division of Chest Medicine, Department of Internal Medicine, Changhua Hospital, Ministry of Health and Welfare, Changhua, 513, Taiwan.; Institute of Medicine, Chung Shan Medical University, Taichung, 402, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+CB%22">Lin CB</searchLink>; Division of Chest Medicine, Department of Internal Medicine, Hualien Tzu Chi Hospital, Hualien, 970, Taiwan.; School of Medicine, Tzu Chi University, Hualien, 970, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chien+ST%22">Chien ST</searchLink>; Chest Hospital, Ministry of Health and Welfare, Tainan, 701, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lee+CH%22">Lee CH</searchLink>; Division of Pulmonary Medicine, Department of Internal Medicine, Wan Fang Hospital, Taipei Medical University, 111 Hsin-Long Road, Section 3, Taipei, 116, Taiwan.; Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 110, Taiwan.<br /><searchLink fieldCode="AU" term="%22Yu+MC%22">Yu MC</searchLink>; Division of Pulmonary Medicine, Department of Internal Medicine, Wan Fang Hospital, Taipei Medical University, 111 Hsin-Long Road, Section 3, Taipei, 116, Taiwan.; School of Respiratory Therapy, College of Medicine, Taipei Medical University, Taipei, 110, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lee+JJ%22">Lee JJ</searchLink>; Division of Chest Medicine, Department of Internal Medicine, Hualien Tzu Chi Hospital, Hualien, 970, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chiang+CY%22">Chiang CY</searchLink>; Division of Pulmonary Medicine, Department of Internal Medicine, Wan Fang Hospital, Taipei Medical University, 111 Hsin-Long Road, Section 3, Taipei, 116, Taiwan. cychiang@theunion.org.; Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 110, Taiwan. cychiang@theunion.org.
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  Data: <searchLink fieldCode="JN" term="%22101563288%22">Scientific reports</searchLink> [Sci Rep] 2026 Feb 21; Vol. 16 (1). <i>Date of Electronic Publication: </i>2026 Feb 21.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101563288 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2045-2322 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220452322%22">20452322 </searchLink><i>NLM ISO Abbreviation: </i>Sci Rep <i>Subsets: </i>MEDLINE
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        Value: 10.1038/s41598-026-39022-4
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              Text: 2026 Feb 21
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