Clinical relevance of mosaic variants detected by exome sequencing.

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Bibliographic Details
Title: Clinical relevance of mosaic variants detected by exome sequencing.
Authors: Ghosh R; Centralized Sequencing Program, Division of Intramural Research, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, Md. Electronic address: rajarshi.ghosh@nih.gov., Fazal Z; Bioinformatics and Computational Biosciences Branch, Office of Cyber Infrastructure and Computational Biology, NIAID, NIH, Bethesda, Md., Oler AJ; Bioinformatics and Computational Biosciences Branch, Office of Cyber Infrastructure and Computational Biology, NIAID, NIH, Bethesda, Md., Tokita MJ; Centralized Sequencing Program, Division of Intramural Research, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, Md., Lewis KL; Centralized Sequencing Program, Division of Intramural Research, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, Md., Paul AJ; Department of Pediatrics, Division of Rheumatology & Immunology, Washington University School of Medicine in St Louis, St Louis, Mo., Schmitz EG; Department of Pediatrics, Division of Rheumatology & Immunology, Washington University School of Medicine in St Louis, St Louis, Mo., Saucier N; Department of Pediatrics, Division of Rheumatology & Immunology, Washington University School of Medicine in St Louis, St Louis, Mo., Yan J; Centralized Sequencing Program, Division of Intramural Research, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, Md., Kamen M; Centralized Sequencing Program, Division of Intramural Research, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, Md., Seifert BA; Centralized Sequencing Program, Division of Intramural Research, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, Md., Klion AD; Human Eosinophil Section, Laboratory of Parasitic Diseases, NIAID, NIH, Bethesda, Md., Khoury P; Human Eosinophil Section, Laboratory of Parasitic Diseases, NIAID, NIH, Bethesda, Md., Delmonte OM; Immune Deficiency Genetics Diseases Section, Laboratory of Clinical Immunology and Microbiology, NIAID, NIH, Bethesda, Md., Notarangelo LD; Immune Deficiency Genetics Diseases Section, Laboratory of Clinical Immunology and Microbiology, NIAID, NIH, Bethesda, Md., Freeman AF; Immunopathogenesis Section, Laboratory of Clinical Immunology and Microbiology, NIAID, NIH, Bethesda, Md., Zerbe CS; Immunopathogenesis Section, Laboratory of Clinical Immunology and Microbiology, NIAID, NIH, Bethesda, Md., Uzel G; Immunopathogenesis Section, Laboratory of Clinical Immunology and Microbiology, NIAID, NIH, Bethesda, Md., Metcalfe DD; Mast Cell Biology Section, Laboratory of Allergic Diseases, NIAID, NIH, Bethesda, Md., Komarow HD; Mast Cell Biology Section, Laboratory of Allergic Diseases, NIAID, NIH, Bethesda, Md., Carter MC; Mast Cell Biology Section, Laboratory of Allergic Diseases, NIAID, NIH, Bethesda, Md., McDermott DH; Molecular Signaling Section, Laboratory of Molecular Immunology, NIAID, NIH, Bethesda, Md., Murphy PM; Molecular Signaling Section, Laboratory of Molecular Immunology, NIAID, NIH, Bethesda, Md., Olivier KN; Division of Pulmonary Diseases and Critical Care Medicine, University of North Carolina, Chapel Hill, NC., Fuss I; Mucosal Immunity Section, Laboratory of Clinical Immunology and Microbiology, NIAID, NIH, Bethesda, Md., Strober W; Mucosal Immunity Section, Laboratory of Clinical Immunology and Microbiology, NIAID, NIH, Bethesda, Md., Rao VK; Primary Immune Deficiency Clinic (ALPS Clinic), Laboratory of Clinical Immunology and Microbiology, NIAID, NIH, Bethesda, Md., Bergerson JRE; Primary Immune Deficiency Clinic, Laboratory of Clinical Immunology and Microbiology, NIAID, NIH, Bethesda, Md., Almeida de Jesus A; Translational Autoinflammatory Disease Studies Unit, Laboratory of Clinical Immunology and Microbiology, NIAID, NIH, Bethesda, Md., Goldbach-Mansky R; Translational Autoinflammatory Disease Studies Unit, Laboratory of Clinical Immunology and Microbiology, NIAID, NIH, Bethesda, Md., Al-Herz W; Department of Pediatrics, College of Medicine, Kuwait University, Kuwait City, Kuwait., Holland SM; Immunopathogenesis Section, Laboratory of Clinical Immunology and Microbiology, NIAID, NIH, Bethesda, Md., Cooper MA; Department of Pediatrics, Division of Rheumatology & Immunology, Washington University School of Medicine in St Louis, St Louis, Mo., Similuk MN; Centralized Sequencing Program, Division of Intramural Research, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, Md., Walkiewicz MA; Centralized Sequencing Program, Division of Intramural Research, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, Md.
Corporate Authors: NIAID Centralized Sequencing Program
Source: The Journal of allergy and clinical immunology [J Allergy Clin Immunol] 2026 May; Vol. 157 (5), pp. 1195-1205. Date of Electronic Publication: 2026 Feb 20.
Publication Type: Journal Article
Journal Info: Publisher: Mosby Country of Publication: United States NLM ID: 1275002 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-6825 (Electronic) Linking ISSN: 00916749 NLM ISO Abbreviation: J Allergy Clin Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1097-6825
DOI:10.1016/j.jaci.2026.02.011