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Modeling mitochondrial inheritance enables high-precision single-cell lineage tracing in humans.

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Title: Modeling mitochondrial inheritance enables high-precision single-cell lineage tracing in humans.
Authors: Gao T; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.; Howard Hughes Medical Institute, Boston, MA, USA.; Broad Institute of MIT and Harvard, Boston, MA, USA., Weng C; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.; Howard Hughes Medical Institute, Boston, MA, USA.; Broad Institute of MIT and Harvard, Boston, MA, USA.; Whitehead Institute for Biomedical Research, Cambridge, MA, USA.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA., Johnson I; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.; Howard Hughes Medical Institute, Boston, MA, USA.; Broad Institute of MIT and Harvard, Boston, MA, USA., Poeschla M; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.; Howard Hughes Medical Institute, Boston, MA, USA.; Broad Institute of MIT and Harvard, Boston, MA, USA., Gudera J; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.; Howard Hughes Medical Institute, Boston, MA, USA.; Broad Institute of MIT and Harvard, Boston, MA, USA., King E; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.; Howard Hughes Medical Institute, Boston, MA, USA.; Broad Institute of MIT and Harvard, Boston, MA, USA., Rouya C; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.; Howard Hughes Medical Institute, Boston, MA, USA.; Broad Institute of MIT and Harvard, Boston, MA, USA., Donovan A; Branch Biosciences, Cambridge, MA, USA., Bourke L; Branch Biosciences, Cambridge, MA, USA., Shao Y; Branch Biosciences, Cambridge, MA, USA., Marquez E; Branch Biosciences, Cambridge, MA, USA., Tyagi R; Branch Biosciences, Cambridge, MA, USA., Zon LI; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.; Howard Hughes Medical Institute, Boston, MA, USA.; Harvard Stem Cell Institute, Cambridge, MA, USA., Weissman JS; Howard Hughes Medical Institute, Boston, MA, USA.; Whitehead Institute for Biomedical Research, Cambridge, MA, USA.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA., Sankaran VG; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.; Howard Hughes Medical Institute, Boston, MA, USA.; Broad Institute of MIT and Harvard, Boston, MA, USA.; Harvard Stem Cell Institute, Cambridge, MA, USA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2026 Feb 18. Date of Electronic Publication: 2026 Feb 18.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Gao+T%22">Gao T</searchLink>; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.; Howard Hughes Medical Institute, Boston, MA, USA.; Broad Institute of MIT and Harvard, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Weng+C%22">Weng C</searchLink>; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.; Howard Hughes Medical Institute, Boston, MA, USA.; Broad Institute of MIT and Harvard, Boston, MA, USA.; Whitehead Institute for Biomedical Research, Cambridge, MA, USA.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Johnson+I%22">Johnson I</searchLink>; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.; Howard Hughes Medical Institute, Boston, MA, USA.; Broad Institute of MIT and Harvard, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Poeschla+M%22">Poeschla M</searchLink>; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.; Howard Hughes Medical Institute, Boston, MA, USA.; Broad Institute of MIT and Harvard, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Gudera+J%22">Gudera J</searchLink>; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.; Howard Hughes Medical Institute, Boston, MA, USA.; Broad Institute of MIT and Harvard, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22King+E%22">King E</searchLink>; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.; Howard Hughes Medical Institute, Boston, MA, USA.; Broad Institute of MIT and Harvard, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Rouya+C%22">Rouya C</searchLink>; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.; Howard Hughes Medical Institute, Boston, MA, USA.; Broad Institute of MIT and Harvard, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Donovan+A%22">Donovan A</searchLink>; Branch Biosciences, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Bourke+L%22">Bourke L</searchLink>; Branch Biosciences, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Shao+Y%22">Shao Y</searchLink>; Branch Biosciences, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Marquez+E%22">Marquez E</searchLink>; Branch Biosciences, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Tyagi+R%22">Tyagi R</searchLink>; Branch Biosciences, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Zon+LI%22">Zon LI</searchLink>; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.; Howard Hughes Medical Institute, Boston, MA, USA.; Harvard Stem Cell Institute, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Weissman+JS%22">Weissman JS</searchLink>; Howard Hughes Medical Institute, Boston, MA, USA.; Whitehead Institute for Biomedical Research, Cambridge, MA, USA.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Sankaran+VG%22">Sankaran VG</searchLink>; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.; Howard Hughes Medical Institute, Boston, MA, USA.; Broad Institute of MIT and Harvard, Boston, MA, USA.; Harvard Stem Cell Institute, Cambridge, MA, USA.
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        Value: 10.64898/2026.02.12.705660
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        Text: English
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