Genome-wide association study of corneal dystrophy uncovers novel risk loci and enables improved polygenic prediction of Fuchs endothelial corneal dystrophy.

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Bibliographic Details
Title: Genome-wide association study of corneal dystrophy uncovers novel risk loci and enables improved polygenic prediction of Fuchs endothelial corneal dystrophy.
Authors: Insawang B; Statistical Genetics Lab, QIMR Berghofer Medical Research Institute, Herston, Brisbane, QLD, Australia.; Faculty of Medicine, University of Queensland, Brisbane, QLD, Australia., Mackey DA; Centre for Ophthalmology and Visual Science, University of Western Australia, Lions Eye Institute, Perth, Western Australia, Australia., Hewitt AW; Centre for Ophthalmology and Visual Science, University of Western Australia, Lions Eye Institute, Perth, Western Australia, Australia; Menzies Institute for Medical Research, University of Tasmania, Hobart, Tasmania, Australia., Craig JE; Department of Ophthalmology, Flinders Health and Medical Research Institute, Flinders University, Adelaide, South Australia, Australia., Mills R; Department of Ophthalmology, Flinders Health and Medical Research Institute, Flinders University, Adelaide, South Australia, Australia., Gharahkhani P; Statistical Genetics Lab, QIMR Berghofer Medical Research Institute, Herston, Brisbane, QLD, Australia.; Faculty of Medicine, University of Queensland, Brisbane, QLD, Australia.; School of Biomedical Sciences, Queensland University of Technology, Brisbane, Queensland, Australia., MacGregor S; Statistical Genetics Lab, QIMR Berghofer Medical Research Institute, Herston, Brisbane, QLD, Australia.
Source: MedRxiv : the preprint server for health sciences [medRxiv] 2026 Feb 15. Date of Electronic Publication: 2026 Feb 15.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101767986 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: medRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
DOI:10.64898/2026.02.10.26345409