Strategic selection of MDM2 inhibitors enhances the efficacy of FAK inhibition in mesothelioma based on TP53 genotype.
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| Title: | Strategic selection of MDM2 inhibitors enhances the efficacy of FAK inhibition in mesothelioma based on TP53 genotype. |
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| Authors: | Ning X; Division of Pathology and Cell Therapy, Chiba Cancer Center Research Institute, Chiba, Japan.; Laboratory of Molecular Cell Biology, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba, Japan., Nguyễn TTT; Division of Pathology and Cell Therapy, Chiba Cancer Center Research Institute, Chiba, Japan.; Department of Molecular Biology and Oncology, Graduate School of Medicine, Chiba University, Chiba, Japan.; Division of Medical Biotechnology, Biotechnology Center of Ho Chi Minh City, Ho Chi Minh, Vietnam., Morinaga T; Division of Pathology and Cell Therapy, Chiba Cancer Center Research Institute, Chiba, Japan., Tada Y; Department of Pulmonary Medicine, International University of Health and Welfare, Narita, Japan., Shimada H; Department of Surgery, Graduate School of Medicine, Toho University, Tokyo Japan., Hiroshima K; Department of Advanced Biomedical Data Science, Graduate School of Medicine, Chiba University, Chiba Japan.; Department of Pathology, Tokyo Women's Medical University, Yachiyo Medical Center, Yachiyo, Japan.; Satsukidai Hospital, Sodegaura, Japan., Yamaguchi N; Laboratory of Molecular Cell Biology, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba, Japan., Tagawa M; Department of Advanced Biomedical Data Science, Graduate School of Medicine, Chiba University, Chiba Japan.; Funabashi Orthopaedic Hospital, Funabashi, Japan. |
| Source: | PloS one [PLoS One] 2026 Feb 23; Vol. 21 (2), pp. e0343551. Date of Electronic Publication: 2026 Feb 23 (Print Publication: 2026). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1932-6203 |
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| DOI: | 10.1371/journal.pone.0343551 |
