Bifidobacterium longum and prebiotic interventions restore early-life high-fat/high-sugar diet-induced alterations in feeding behavior in adult mice.

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Title: Bifidobacterium longum and prebiotic interventions restore early-life high-fat/high-sugar diet-induced alterations in feeding behavior in adult mice.
Authors: Cuesta-Marti C; Department of Anatomy and Neuroscience, University College Cork, Cork, Ireland. CCuestaMarti@ucc.ie.; APC Microbiome Ireland, Cork, Ireland. CCuestaMarti@ucc.ie., Ponce-España E; Department of Anatomy and Neuroscience, University College Cork, Cork, Ireland.; Instituto de Biomedicina de Sevilla, IBiS, Universidad de Sevilla, HUVR, Junta de Andalucía, CSIC, Sevilla, Spain.; Departamento de Bioquímica Médica y Biología Molecular e Inmunología, Facultad de Medicina, Universidad de Sevilla, Sevilla, Spain., Uhlig F; Department of Anatomy and Neuroscience, University College Cork, Cork, Ireland.; APC Microbiome Ireland, Cork, Ireland.; Department of Pharmacology and Therapeutics, University College, Cork, Ireland., Stoltenborg I; Department of Physiology/Endocrine, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden., Wasiewska LA; APC Microbiome Ireland, Cork, Ireland.; The Life Sciences Interface Group, Tyndall National Institute, Lee Maltings Complex, Cork, Ireland., Kareem L; APC Microbiome Ireland, Cork, Ireland., Hedayatpour D; APC Microbiome Ireland, Cork, Ireland.; Teagasc Food Research Centre, Moorepark, Fermoy, Ireland., Olavarría-Ramírez L; Department of Anatomy and Neuroscience, University College Cork, Cork, Ireland.; APC Microbiome Ireland, Cork, Ireland., Rosell-Cardona C; APC Microbiome Ireland, Cork, Ireland., Bastiaanssen TFS; APC Microbiome Ireland, Cork, Ireland., Tofani GSS; Department of Anatomy and Neuroscience, University College Cork, Cork, Ireland.; APC Microbiome Ireland, Cork, Ireland., Valderrama B; Department of Anatomy and Neuroscience, University College Cork, Cork, Ireland.; APC Microbiome Ireland, Cork, Ireland., Vlckova K; APC Microbiome Ireland, Cork, Ireland., Dickson SL; Department of Physiology/Endocrine, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden., Lavelle A; Department of Anatomy and Neuroscience, University College Cork, Cork, Ireland.; APC Microbiome Ireland, Cork, Ireland., Stanton C; APC Microbiome Ireland, Cork, Ireland.; Teagasc Food Research Centre, Moorepark, Fermoy, Ireland., Ross RP; APC Microbiome Ireland, Cork, Ireland., Cryan JF; Department of Anatomy and Neuroscience, University College Cork, Cork, Ireland.; APC Microbiome Ireland, Cork, Ireland., Dinan TG; APC Microbiome Ireland, Cork, Ireland.; Department of Psychiatry and Neurobehavioral Science, University College Cork, Cork, Ireland., Clarke G; APC Microbiome Ireland, Cork, Ireland.; Department of Psychiatry and Neurobehavioral Science, University College Cork, Cork, Ireland., O'Mahony SM; Department of Anatomy and Neuroscience, University College Cork, Cork, Ireland.; APC Microbiome Ireland, Cork, Ireland., Schellekens H; Department of Anatomy and Neuroscience, University College Cork, Cork, Ireland. h.schellekens@ucc.ie.; APC Microbiome Ireland, Cork, Ireland. h.schellekens@ucc.ie.
Source: Nature communications [Nat Commun] 2026 Feb 24; Vol. 17 (1). Date of Electronic Publication: 2026 Feb 24.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-026-68968-2