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Bifidobacterium longum and prebiotic interventions restore early-life high-fat/high-sugar diet-induced alterations in feeding behavior in adult mice.

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Title: Bifidobacterium longum and prebiotic interventions restore early-life high-fat/high-sugar diet-induced alterations in feeding behavior in adult mice.
Authors: Cuesta-Marti C; Department of Anatomy and Neuroscience, University College Cork, Cork, Ireland. CCuestaMarti@ucc.ie.; APC Microbiome Ireland, Cork, Ireland. CCuestaMarti@ucc.ie., Ponce-España E; Department of Anatomy and Neuroscience, University College Cork, Cork, Ireland.; Instituto de Biomedicina de Sevilla, IBiS, Universidad de Sevilla, HUVR, Junta de Andalucía, CSIC, Sevilla, Spain.; Departamento de Bioquímica Médica y Biología Molecular e Inmunología, Facultad de Medicina, Universidad de Sevilla, Sevilla, Spain., Uhlig F; Department of Anatomy and Neuroscience, University College Cork, Cork, Ireland.; APC Microbiome Ireland, Cork, Ireland.; Department of Pharmacology and Therapeutics, University College, Cork, Ireland., Stoltenborg I; Department of Physiology/Endocrine, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden., Wasiewska LA; APC Microbiome Ireland, Cork, Ireland.; The Life Sciences Interface Group, Tyndall National Institute, Lee Maltings Complex, Cork, Ireland., Kareem L; APC Microbiome Ireland, Cork, Ireland., Hedayatpour D; APC Microbiome Ireland, Cork, Ireland.; Teagasc Food Research Centre, Moorepark, Fermoy, Ireland., Olavarría-Ramírez L; Department of Anatomy and Neuroscience, University College Cork, Cork, Ireland.; APC Microbiome Ireland, Cork, Ireland., Rosell-Cardona C; APC Microbiome Ireland, Cork, Ireland., Bastiaanssen TFS; APC Microbiome Ireland, Cork, Ireland., Tofani GSS; Department of Anatomy and Neuroscience, University College Cork, Cork, Ireland.; APC Microbiome Ireland, Cork, Ireland., Valderrama B; Department of Anatomy and Neuroscience, University College Cork, Cork, Ireland.; APC Microbiome Ireland, Cork, Ireland., Vlckova K; APC Microbiome Ireland, Cork, Ireland., Dickson SL; Department of Physiology/Endocrine, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden., Lavelle A; Department of Anatomy and Neuroscience, University College Cork, Cork, Ireland.; APC Microbiome Ireland, Cork, Ireland., Stanton C; APC Microbiome Ireland, Cork, Ireland.; Teagasc Food Research Centre, Moorepark, Fermoy, Ireland., Ross RP; APC Microbiome Ireland, Cork, Ireland., Cryan JF; Department of Anatomy and Neuroscience, University College Cork, Cork, Ireland.; APC Microbiome Ireland, Cork, Ireland., Dinan TG; APC Microbiome Ireland, Cork, Ireland.; Department of Psychiatry and Neurobehavioral Science, University College Cork, Cork, Ireland., Clarke G; APC Microbiome Ireland, Cork, Ireland.; Department of Psychiatry and Neurobehavioral Science, University College Cork, Cork, Ireland., O'Mahony SM; Department of Anatomy and Neuroscience, University College Cork, Cork, Ireland.; APC Microbiome Ireland, Cork, Ireland., Schellekens H; Department of Anatomy and Neuroscience, University College Cork, Cork, Ireland. h.schellekens@ucc.ie.; APC Microbiome Ireland, Cork, Ireland. h.schellekens@ucc.ie.
Source: Nature communications [Nat Commun] 2026 Feb 24; Vol. 17 (1). Date of Electronic Publication: 2026 Feb 24.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Bifidobacterium longum and prebiotic interventions restore early-life high-fat/high-sugar diet-induced alterations in feeding behavior in adult mice.
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  Data: <searchLink fieldCode="AU" term="%22Cuesta-Marti+C%22">Cuesta-Marti C</searchLink>; Department of Anatomy and Neuroscience, University College Cork, Cork, Ireland. CCuestaMarti@ucc.ie.; APC Microbiome Ireland, Cork, Ireland. CCuestaMarti@ucc.ie.<br /><searchLink fieldCode="AU" term="%22Ponce-España+E%22">Ponce-España E</searchLink>; Department of Anatomy and Neuroscience, University College Cork, Cork, Ireland.; Instituto de Biomedicina de Sevilla, IBiS, Universidad de Sevilla, HUVR, Junta de Andalucía, CSIC, Sevilla, Spain.; Departamento de Bioquímica Médica y Biología Molecular e Inmunología, Facultad de Medicina, Universidad de Sevilla, Sevilla, Spain.<br /><searchLink fieldCode="AU" term="%22Uhlig+F%22">Uhlig F</searchLink>; Department of Anatomy and Neuroscience, University College Cork, Cork, Ireland.; APC Microbiome Ireland, Cork, Ireland.; Department of Pharmacology and Therapeutics, University College, Cork, Ireland.<br /><searchLink fieldCode="AU" term="%22Stoltenborg+I%22">Stoltenborg I</searchLink>; Department of Physiology/Endocrine, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden.<br /><searchLink fieldCode="AU" term="%22Wasiewska+LA%22">Wasiewska LA</searchLink>; APC Microbiome Ireland, Cork, Ireland.; The Life Sciences Interface Group, Tyndall National Institute, Lee Maltings Complex, Cork, Ireland.<br /><searchLink fieldCode="AU" term="%22Kareem+L%22">Kareem L</searchLink>; APC Microbiome Ireland, Cork, Ireland.<br /><searchLink fieldCode="AU" term="%22Hedayatpour+D%22">Hedayatpour D</searchLink>; APC Microbiome Ireland, Cork, Ireland.; Teagasc Food Research Centre, Moorepark, Fermoy, Ireland.<br /><searchLink fieldCode="AU" term="%22Olavarría-Ramírez+L%22">Olavarría-Ramírez L</searchLink>; Department of Anatomy and Neuroscience, University College Cork, Cork, Ireland.; APC Microbiome Ireland, Cork, Ireland.<br /><searchLink fieldCode="AU" term="%22Rosell-Cardona+C%22">Rosell-Cardona C</searchLink>; APC Microbiome Ireland, Cork, Ireland.<br /><searchLink fieldCode="AU" term="%22Bastiaanssen+TFS%22">Bastiaanssen TFS</searchLink>; APC Microbiome Ireland, Cork, Ireland.<br /><searchLink fieldCode="AU" term="%22Tofani+GSS%22">Tofani GSS</searchLink>; Department of Anatomy and Neuroscience, University College Cork, Cork, Ireland.; APC Microbiome Ireland, Cork, Ireland.<br /><searchLink fieldCode="AU" term="%22Valderrama+B%22">Valderrama B</searchLink>; Department of Anatomy and Neuroscience, University College Cork, Cork, Ireland.; APC Microbiome Ireland, Cork, Ireland.<br /><searchLink fieldCode="AU" term="%22Vlckova+K%22">Vlckova K</searchLink>; APC Microbiome Ireland, Cork, Ireland.<br /><searchLink fieldCode="AU" term="%22Dickson+SL%22">Dickson SL</searchLink>; Department of Physiology/Endocrine, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden.<br /><searchLink fieldCode="AU" term="%22Lavelle+A%22">Lavelle A</searchLink>; Department of Anatomy and Neuroscience, University College Cork, Cork, Ireland.; APC Microbiome Ireland, Cork, Ireland.<br /><searchLink fieldCode="AU" term="%22Stanton+C%22">Stanton C</searchLink>; APC Microbiome Ireland, Cork, Ireland.; Teagasc Food Research Centre, Moorepark, Fermoy, Ireland.<br /><searchLink fieldCode="AU" term="%22Ross+RP%22">Ross RP</searchLink>; APC Microbiome Ireland, Cork, Ireland.<br /><searchLink fieldCode="AU" term="%22Cryan+JF%22">Cryan JF</searchLink>; Department of Anatomy and Neuroscience, University College Cork, Cork, Ireland.; APC Microbiome Ireland, Cork, Ireland.<br /><searchLink fieldCode="AU" term="%22Dinan+TG%22">Dinan TG</searchLink>; APC Microbiome Ireland, Cork, Ireland.; Department of Psychiatry and Neurobehavioral Science, University College Cork, Cork, Ireland.<br /><searchLink fieldCode="AU" term="%22Clarke+G%22">Clarke G</searchLink>; APC Microbiome Ireland, Cork, Ireland.; Department of Psychiatry and Neurobehavioral Science, University College Cork, Cork, Ireland.<br /><searchLink fieldCode="AU" term="%22O'Mahony+SM%22">O'Mahony SM</searchLink>; Department of Anatomy and Neuroscience, University College Cork, Cork, Ireland.; APC Microbiome Ireland, Cork, Ireland.<br /><searchLink fieldCode="AU" term="%22Schellekens+H%22">Schellekens H</searchLink>; Department of Anatomy and Neuroscience, University College Cork, Cork, Ireland. h.schellekens@ucc.ie.; APC Microbiome Ireland, Cork, Ireland. h.schellekens@ucc.ie.
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