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Personalized signaling pathway analysis of gastrointestinal tumors for patient stratification and drug target evaluation using clinically derived core biopsies.

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Title: Personalized signaling pathway analysis of gastrointestinal tumors for patient stratification and drug target evaluation using clinically derived core biopsies.
Authors: Stahl A; NMI Natural and Medical Sciences Institute at the University of Tübingen, Reutlingen, Germany. aaron.m.stahl@gmx.de.; Institute of Biomedical Engineering, Department for Medical Technologies and Regenerative Medicine, University of Tübingen, Tübingen, Germany. aaron.m.stahl@gmx.de., Büringer K; Department of Internal Medicine I, University Hospital Tübingen, Tübingen, Germany., Missios P; Department of Internal Medicine I, University Hospital Tübingen, Tübingen, Germany.; Center for Personalized Medicine, Eberhard-Karls University, Tübingen, Germany., Hoffmann T; Department of Internal Medicine I, University Hospital Tübingen, Tübingen, Germany., Mattern S; Department of Pathology and Neuropathology, University Hospital Tübingen, Tübingen, Germany., Singer S; Department of Pathology and Neuropathology, University Hospital Tübingen, Tübingen, Germany., Schäfer-Ruoff F; NMI Natural and Medical Sciences Institute at the University of Tübingen, Reutlingen, Germany., Malek NP; Department of Internal Medicine I, University Hospital Tübingen, Tübingen, Germany.; Center for Personalized Medicine, Eberhard-Karls University, Tübingen, Germany.; M3-Research Center for Malignome, Metabolome and Microbiome, Eberhard-Karls University, Tübingen, Germany., Schenke-Layland K; NMI Natural and Medical Sciences Institute at the University of Tübingen, Reutlingen, Germany.; Institute of Biomedical Engineering, Department for Medical Technologies and Regenerative Medicine, University of Tübingen, Tübingen, Germany., Bitzer M; Department of Internal Medicine I, University Hospital Tübingen, Tübingen, Germany. m.bitzer@med.uni-tuebingen.de.; Center for Personalized Medicine, Eberhard-Karls University, Tübingen, Germany. m.bitzer@med.uni-tuebingen.de.; M3-Research Center for Malignome, Metabolome and Microbiome, Eberhard-Karls University, Tübingen, Germany. m.bitzer@med.uni-tuebingen.de., Templin MF; NMI Natural and Medical Sciences Institute at the University of Tübingen, Reutlingen, Germany. markus.templin@nmi.de.
Source: NPJ precision oncology [NPJ Precis Oncol] 2026 Feb 25; Vol. 10 (1). Date of Electronic Publication: 2026 Feb 25.
Publication Type: Journal Article
Journal Info: Publisher: Springer Nature Country of Publication: England NLM ID: 101708166 Publication Model: Electronic Cited Medium: Print ISSN: 2397-768X (Print) Linking ISSN: 2397768X NLM ISO Abbreviation: NPJ Precis Oncol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Personalized signaling pathway analysis of gastrointestinal tumors for patient stratification and drug target evaluation using clinically derived core biopsies.
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  Data: <searchLink fieldCode="AU" term="%22Stahl+A%22">Stahl A</searchLink>; NMI Natural and Medical Sciences Institute at the University of Tübingen, Reutlingen, Germany. aaron.m.stahl@gmx.de.; Institute of Biomedical Engineering, Department for Medical Technologies and Regenerative Medicine, University of Tübingen, Tübingen, Germany. aaron.m.stahl@gmx.de.<br /><searchLink fieldCode="AU" term="%22Büringer+K%22">Büringer K</searchLink>; Department of Internal Medicine I, University Hospital Tübingen, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Missios+P%22">Missios P</searchLink>; Department of Internal Medicine I, University Hospital Tübingen, Tübingen, Germany.; Center for Personalized Medicine, Eberhard-Karls University, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Hoffmann+T%22">Hoffmann T</searchLink>; Department of Internal Medicine I, University Hospital Tübingen, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Mattern+S%22">Mattern S</searchLink>; Department of Pathology and Neuropathology, University Hospital Tübingen, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Singer+S%22">Singer S</searchLink>; Department of Pathology and Neuropathology, University Hospital Tübingen, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Schäfer-Ruoff+F%22">Schäfer-Ruoff F</searchLink>; NMI Natural and Medical Sciences Institute at the University of Tübingen, Reutlingen, Germany.<br /><searchLink fieldCode="AU" term="%22Malek+NP%22">Malek NP</searchLink>; Department of Internal Medicine I, University Hospital Tübingen, Tübingen, Germany.; Center for Personalized Medicine, Eberhard-Karls University, Tübingen, Germany.; M3-Research Center for Malignome, Metabolome and Microbiome, Eberhard-Karls University, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Schenke-Layland+K%22">Schenke-Layland K</searchLink>; NMI Natural and Medical Sciences Institute at the University of Tübingen, Reutlingen, Germany.; Institute of Biomedical Engineering, Department for Medical Technologies and Regenerative Medicine, University of Tübingen, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Bitzer+M%22">Bitzer M</searchLink>; Department of Internal Medicine I, University Hospital Tübingen, Tübingen, Germany. m.bitzer@med.uni-tuebingen.de.; Center for Personalized Medicine, Eberhard-Karls University, Tübingen, Germany. m.bitzer@med.uni-tuebingen.de.; M3-Research Center for Malignome, Metabolome and Microbiome, Eberhard-Karls University, Tübingen, Germany. m.bitzer@med.uni-tuebingen.de.<br /><searchLink fieldCode="AU" term="%22Templin+MF%22">Templin MF</searchLink>; NMI Natural and Medical Sciences Institute at the University of Tübingen, Reutlingen, Germany. markus.templin@nmi.de.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+Nature%22">Springer Nature </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101708166 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>2397-768X (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%222397768X%22">2397768X </searchLink><i>NLM ISO Abbreviation: </i>NPJ Precis Oncol <i>Subsets: </i>PubMed not MEDLINE
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              Text: 2026 Feb 25
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