Real-world longitudinal validation of high-income-country-derived sepsis endotypes in sub-Saharan Africa: a nested prospective multicenter study.

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Title: Real-world longitudinal validation of high-income-country-derived sepsis endotypes in sub-Saharan Africa: a nested prospective multicenter study.
Authors: Turgman O; Center for Infection and Molecular Medicine, Amsterdam UMC, Amsterdam Institute for Infection and Immunity, University of Amsterdam, Amsterdam, The Netherlands. o.turgman@amsterdamumc.nl., Butler JM; Center for Infection and Molecular Medicine, Amsterdam UMC, Amsterdam Institute for Infection and Immunity, University of Amsterdam, Amsterdam, The Netherlands., Haguma P; Walimu, Kampala, Uganda., Nyesiga S; Walimu, Kampala, Uganda., Phulusa J; Malawi-Liverpool Wellcome, Blantyre, Malawi., Carey L; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK., Rylance J; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK., van der Poll T; Center for Infection and Molecular Medicine, Amsterdam UMC, Amsterdam Institute for Infection and Immunity, University of Amsterdam, Amsterdam, The Netherlands.; Department of Medicine, Division of Infectious Diseases, Amsterdam UMC, location Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands., Wiersinga WJ; Center for Infection and Molecular Medicine, Amsterdam UMC, Amsterdam Institute for Infection and Immunity, University of Amsterdam, Amsterdam, The Netherlands.; Department of Medicine, Division of Infectious Diseases, Amsterdam UMC, location Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands., Jacob ST; Walimu, Kampala, Uganda.; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK.
Source: Critical care (London, England) [Crit Care] 2026 Feb 25; Vol. 30 (1). Date of Electronic Publication: 2026 Feb 25.
Publication Type: Journal Article; Multicenter Study
Journal Info: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 9801902 Publication Model: Electronic Cited Medium: Internet ISSN: 1466-609X (Electronic) Linking ISSN: 13648535 NLM ISO Abbreviation: Crit Care Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1466-609X
DOI:10.1186/s13054-026-05901-5