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Metabolome analysis identified exogenous cholesterol within lipid rafts that activate the Akt/mTOR signaling pathway in epithelial ovarian cancer.

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Title: Metabolome analysis identified exogenous cholesterol within lipid rafts that activate the Akt/mTOR signaling pathway in epithelial ovarian cancer.
Authors: Sakaguchi-Mukaida H; Department of Obstetrics and Gynecology, The University of Osaka Graduate School of Medicine, Suita, Osaka, Japan., Hiramatsu K; Department of Obstetrics and Gynecology, The University of Osaka Graduate School of Medicine, Suita, Osaka, Japan., Masuda T; Department of Obstetrics and Gynecology, The University of Osaka Graduate School of Medicine, Suita, Osaka, Japan., Kakuda M; Department of Obstetrics and Gynecology, The University of Osaka Graduate School of Medicine, Suita, Osaka, Japan., Nakagawa S; Department of Obstetrics and Gynecology, The University of Osaka Graduate School of Medicine, Suita, Osaka, Japan., Iwamiya T; Department of Obstetrics and Gynecology, The University of Osaka Graduate School of Medicine, Suita, Osaka, Japan., Matsuzaki S; Department of Obstetrics and Gynecology, The University of Osaka Graduate School of Medicine, Suita, Osaka, Japan., Naka T; Institute for Biomedical Sciences Molecular Pathophysiology, Iwate Medical University, Yahaba-cho, Iwate, Japan., Ueda Y; Department of Obstetrics and Gynecology, The University of Osaka Graduate School of Medicine, Suita, Osaka, Japan., Kimura T; Sakai City Hospital Organization, Sakai, Osaka, Japan., Kodama M; Department of Obstetrics and Gynecology, The University of Osaka Graduate School of Medicine, Suita, Osaka, Japan.
Source: International journal of cancer [Int J Cancer] 2026 Jul 01; Vol. 159 (1), pp. 257-268. Date of Electronic Publication: 2026 Feb 26.
Publication Type: Journal Article
Journal Info: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 0042124 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-0215 (Electronic) Linking ISSN: 00207136 NLM ISO Abbreviation: Int J Cancer Subsets: MEDLINE
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  Data: Metabolome analysis identified exogenous cholesterol within lipid rafts that activate the Akt/mTOR signaling pathway in epithelial ovarian cancer.
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  Data: <searchLink fieldCode="AU" term="%22Sakaguchi-Mukaida+H%22">Sakaguchi-Mukaida H</searchLink>; Department of Obstetrics and Gynecology, The University of Osaka Graduate School of Medicine, Suita, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Hiramatsu+K%22">Hiramatsu K</searchLink>; Department of Obstetrics and Gynecology, The University of Osaka Graduate School of Medicine, Suita, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Masuda+T%22">Masuda T</searchLink>; Department of Obstetrics and Gynecology, The University of Osaka Graduate School of Medicine, Suita, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Kakuda+M%22">Kakuda M</searchLink>; Department of Obstetrics and Gynecology, The University of Osaka Graduate School of Medicine, Suita, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Nakagawa+S%22">Nakagawa S</searchLink>; Department of Obstetrics and Gynecology, The University of Osaka Graduate School of Medicine, Suita, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Iwamiya+T%22">Iwamiya T</searchLink>; Department of Obstetrics and Gynecology, The University of Osaka Graduate School of Medicine, Suita, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Matsuzaki+S%22">Matsuzaki S</searchLink>; Department of Obstetrics and Gynecology, The University of Osaka Graduate School of Medicine, Suita, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Naka+T%22">Naka T</searchLink>; Institute for Biomedical Sciences Molecular Pathophysiology, Iwate Medical University, Yahaba-cho, Iwate, Japan.<br /><searchLink fieldCode="AU" term="%22Ueda+Y%22">Ueda Y</searchLink>; Department of Obstetrics and Gynecology, The University of Osaka Graduate School of Medicine, Suita, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Kimura+T%22">Kimura T</searchLink>; Sakai City Hospital Organization, Sakai, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Kodama+M%22">Kodama M</searchLink>; Department of Obstetrics and Gynecology, The University of Osaka Graduate School of Medicine, Suita, Osaka, Japan.
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  Data: <searchLink fieldCode="JN" term="%220042124%22">International journal of cancer</searchLink> [Int J Cancer] 2026 Jul 01; Vol. 159 (1), pp. 257-268. <i>Date of Electronic Publication: </i>2026 Feb 26.
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              Text: 2026 Jul 01
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