Design, synthesis, and experimental evaluation of rupestonic acid derivatives as novel anti-tumor agents guided by network pharmacology and molecular docking.
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| Title: | Design, synthesis, and experimental evaluation of rupestonic acid derivatives as novel anti-tumor agents guided by network pharmacology and molecular docking. |
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| Authors: | Yusuf A; College of Chemistry and Environmental Science, The Key Laboratory of Xinjiang Native Medicinal and Edible Plant Resources Chemistry, Kashi University, Kashi, China. kashidaxue_abudula@163.com., Adelibieke Q; College of Chemistry and Environmental Science, The Key Laboratory of Xinjiang Native Medicinal and Edible Plant Resources Chemistry, Kashi University, Kashi, China., Tursun E; College of Chemistry and Environmental Science, The Key Laboratory of Xinjiang Native Medicinal and Edible Plant Resources Chemistry, Kashi University, Kashi, China., Yucai Z; College of Chemistry and Environmental Science, The Key Laboratory of Xinjiang Native Medicinal and Edible Plant Resources Chemistry, Kashi University, Kashi, China., Shining Q; College of Chemistry and Environmental Science, The Key Laboratory of Xinjiang Native Medicinal and Edible Plant Resources Chemistry, Kashi University, Kashi, China., Hu L; State Key Laboratory of Biocatalysts and Enzyme Engineering, National & Local Joint Engineering Research Centre of High-Throughput Drug Screening Technology, School of Life Sciences, Hubei University, Wuhan, China., Aierken M; Department of General Practice, Kashi Prefecture Second People's Hospital No. 1, JianKang Road, Kashi, 844000, Xinjiang, China. 3291252060@qq.com., Aobuli A; The Traditional Uygur Medical Hospital of Hotan Prefecture, Hetian, China. 353146200@qq.com., Yumaier A; College of Chemistry and Environmental Science, The Key Laboratory of Xinjiang Native Medicinal and Edible Plant Resources Chemistry, Kashi University, Kashi, China. ablimit0608@163.com., Abudurexiti A; College of Chemistry and Environmental Science, The Key Laboratory of Xinjiang Native Medicinal and Edible Plant Resources Chemistry, Kashi University, Kashi, China. aji_228@163.com. |
| Source: | Scientific reports [Sci Rep] 2026 Feb 26; Vol. 16 (1). Date of Electronic Publication: 2026 Feb 26. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2045-2322 |
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| DOI: | 10.1038/s41598-026-39442-2 |
