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Human Cytomegalovirus Serostatus Defines Cytokine-Based Predictive Signatures in Sepsis.

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Title: Human Cytomegalovirus Serostatus Defines Cytokine-Based Predictive Signatures in Sepsis.
Authors: Krause F; Ruhr University Bochum, Knappschaft Kliniken University Hospital Bochum, Department of Anesthesiology, Intensive Care Medicine and Pain Therapy, 44892 Bochum, Germany., Dyck B; Ruhr University Bochum, Knappschaft Kliniken University Hospital Bochum, Department of Anesthesiology, Intensive Care Medicine and Pain Therapy, Center for Perioperative Precision Medicine, 44892 Bochum, Germany., Kappler K; Ruhr University Bochum, Knappschaft Kliniken University Hospital Bochum, Department of Anesthesiology, Intensive Care Medicine and Pain Therapy, Center for Artificial Intelligence, Medical Informatics and Data Science, 44892 Bochum, Germany., Unterberg M; Ruhr University Bochum, Knappschaft Kliniken University Hospital Bochum, Department of Anesthesiology, Intensive Care Medicine and Pain Therapy, 44892 Bochum, Germany., Nowak H; Ruhr University Bochum, Knappschaft Kliniken University Hospital Bochum, Department of Anesthesiology, Intensive Care Medicine and Pain Therapy, 44892 Bochum, Germany.; Ruhr University Bochum, Knappschaft Kliniken University Hospital Bochum, Department of Anesthesiology, Intensive Care Medicine and Pain Therapy, Center for Artificial Intelligence, Medical Informatics and Data Science, 44892 Bochum, Germany., Rahmel T; Ruhr University Bochum, Knappschaft Kliniken University Hospital Bochum, Department of Anesthesiology, Intensive Care Medicine and Pain Therapy, 44892 Bochum, Germany., Bergmann L; Ruhr University Bochum, Knappschaft Kliniken University Hospital Bochum, Department of Anesthesiology, Intensive Care Medicine and Pain Therapy, 44892 Bochum, Germany., Palmowski L; Ruhr University Bochum, Knappschaft Kliniken University Hospital Bochum, Department of Anesthesiology, Intensive Care Medicine and Pain Therapy, 44892 Bochum, Germany., Westhus B; Ruhr University Bochum, Knappschaft Kliniken University Hospital Bochum, Department of Anesthesiology, Intensive Care Medicine and Pain Therapy, 44892 Bochum, Germany., Wolf A; Ruhr University Bochum, Knappschaft Kliniken University Hospital Bochum, Department of Anesthesiology, Intensive Care Medicine and Pain Therapy, 44892 Bochum, Germany., Busch AV; Ruhr University Bochum, Knappschaft Kliniken University Hospital Bochum, Department of Anesthesiology, Intensive Care Medicine and Pain Therapy, 44892 Bochum, Germany., Sitek B; Ruhr University Bochum, Knappschaft Kliniken University Hospital Bochum, Department of Anesthesiology, Intensive Care Medicine and Pain Therapy, Center for Clinical Proteomic and Metabolomic, 44892 Bochum, Germany.; Ruhr University Bochum, Medical Faculty, Medizinisches Proteom-Center, 44801 Bochum, Germany., Thon P; Ruhr University Bochum, Knappschaft Kliniken University Hospital Bochum, Department of Anesthesiology, Intensive Care Medicine and Pain Therapy, Center for Perioperative Precision Medicine, 44892 Bochum, Germany., Rump K; Ruhr University Bochum, Knappschaft Kliniken University Hospital Bochum, Department of Anesthesiology, Intensive Care Medicine and Pain Therapy, Center for Perioperative Precision Medicine, 44892 Bochum, Germany., Ziehe D; Ruhr University Bochum, Knappschaft Kliniken University Hospital Bochum, Department of Anesthesiology, Intensive Care Medicine and Pain Therapy, Center for Perioperative Precision Medicine, 44892 Bochum, Germany., Wappler F; Department of Anaesthesiology and Critical Care Medicine, Merheim Medical Center, Witten/Herdecke University, 51109 Cologne, Germany., Putensen C; Klinik für Anästhesiologie und Operative Intensivmedizin, Universitätsklinikum Bonn, 53127 Bonn, Germany., Ehrentraut SF; Klinik für Anästhesiologie und Operative Intensivmedizin, Universitätsklinikum Bonn, 53127 Bonn, Germany., Zarbock A; Department of Anesthesiology, Intensive Care and Pain Medicine, University Hospital Münster, 48149 Münster, Germany., Henzler D; Klinikum Herford, Department of Anesthesiology, Surgical Intensive Care, Emergency and Pain Medicine, Ruhr University Bochum, 32049 Herford, Germany., Babel N; Centrum für Translationale Medizin mit Schwerpunkt Immunologie und Transplantation, Marien Hospital Herne, Universitätsklinikum der Ruhr-Universität Bochum, 44625 Herne, Germany., Eisenacher M; Ruhr University Bochum, Medical Faculty, Medizinisches Proteom-Center, 44801 Bochum, Germany.; Ruhr University Bochum, Medical Faculty, CUBiMed.RUB, Core Unit Bioinformatics, 44801 Bochum, Germany.; Ruhr University Bochum, Medical Proteome Analysis, Center for Proteindiagnostics (PRODI), 44801 Bochum, Germany., Marcus K; Ruhr University Bochum, Medical Faculty, Medizinisches Proteom-Center, 44801 Bochum, Germany., Ellger B; Department of Anesthesiology, Intensive Care and Pain Medicine, Klinikum Westfalen, 44309 Dortmund, Germany., Koos B; Ruhr University Bochum, Knappschaft Kliniken University Hospital Bochum, Department of Anesthesiology, Intensive Care Medicine and Pain Therapy, Center for Perioperative Precision Medicine, 44892 Bochum, Germany., Adamzik M; Ruhr University Bochum, Knappschaft Kliniken University Hospital Bochum, Department of Anesthesiology, Intensive Care Medicine and Pain Therapy, 44892 Bochum, Germany., Witowski A; Ruhr University Bochum, Knappschaft Kliniken University Hospital Bochum, Department of Anesthesiology, Intensive Care Medicine and Pain Therapy, 44892 Bochum, Germany.; Ruhr University Bochum, Knappschaft Kliniken University Hospital Bochum, Department of Anesthesiology, Intensive Care Medicine and Pain Therapy, Center for Perioperative Precision Medicine, 44892 Bochum, Germany.
Source: Pathogens (Basel, Switzerland) [Pathogens] 2026 Jan 24; Vol. 15 (2). Date of Electronic Publication: 2026 Jan 24.
Publication Type: Journal Article; Multicenter Study
Journal Info: Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101596317 Publication Model: Electronic Cited Medium: Internet ISSN: 2076-0817 (Electronic) Linking ISSN: 20760817 NLM ISO Abbreviation: Pathogens Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2076-0817
DOI:10.3390/pathogens15020129