Activation of farnesoid X receptor inhibits TMEM16A-mediated chloride secretion in renal collecting duct cells and retards renal cyst progression.
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| Title: | Activation of farnesoid X receptor inhibits TMEM16A-mediated chloride secretion in renal collecting duct cells and retards renal cyst progression. |
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| Authors: | Srimai N; Research Center of Transporter Protein for Medical Innovation, Department of Physiology, Faculty of Science, Mahidol University, Bangkok, Thailand.; Faculty of Medicine, Praboromarajchanok Institute, Ministry of Public Health, Nonthaburi, Thailand., Tonum K; Department of Physiology, Faculty of Pharmacy, Mahidol University, Bangkok, Thailand., Sureram S; Chulabhorn Research Institute, Bangkok, Thailand.; Program in Chemical Sciences, Chulabhorn Graduate Institute, Chulabhorn Royal Academy, Bangkok, Thailand.; Center of Excellence on Environmental Health and Toxicology (EHT), OPS, Ministry of Higher Education, Science, Research and Innovation, Bangkok, Thailand., Tubsuwan A; Institute of Molecular Biosciences, Mahidol University, Nakhon Pathom, Thailand., Kittakoop P; Chulabhorn Research Institute, Bangkok, Thailand.; Program in Chemical Sciences, Chulabhorn Graduate Institute, Chulabhorn Royal Academy, Bangkok, Thailand.; Center of Excellence on Environmental Health and Toxicology (EHT), OPS, Ministry of Higher Education, Science, Research and Innovation, Bangkok, Thailand., Soodvilai S; Research Center of Transporter Protein for Medical Innovation, Department of Physiology, Faculty of Science, Mahidol University, Bangkok, Thailand.; Excellent Center for Drug Discovery, Mahidol University, Bangkok, Thailand. |
| Source: | American journal of physiology. Renal physiology [Am J Physiol Renal Physiol] 2026 Apr 01; Vol. 330 (4), pp. F444-F455. Date of Electronic Publication: 2026 Feb 27. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901990 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1466 (Electronic) Linking ISSN: 15221466 NLM ISO Abbreviation: Am J Physiol Renal Physiol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1522-1466 |
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| DOI: | 10.1152/ajprenal.00370.2025 |
