Immune-adaptive pathogen variation reveals targetable mediators of gram-positive bacterial killing in macrophages.

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Title: Immune-adaptive pathogen variation reveals targetable mediators of gram-positive bacterial killing in macrophages.
Authors: Russell CD; University of Edinburgh Centre for Inflammation Research, Institute for Regeneration and Repair, Edinburgh EH16 4UU, UK.; Baillie-Gifford Pandemic Science Hub, Institute for Regeneration and Repair, The University of Edinburgh, Edinburgh EH16 4UU, UK., Marshall J; University of Edinburgh Centre for Inflammation Research, Institute for Regeneration and Repair, Edinburgh EH16 4UU, UK., McHugh BJ; University of Edinburgh Centre for Inflammation Research, Institute for Regeneration and Repair, Edinburgh EH16 4UU, UK., Michno BJ; Department of Evolutionary Immunology, Institute of Zoology and Biomedical Research, Faculty of Biology, Jagiellonian University, Kraków 31-007, Poland.; Doctoral School of Exact and Natural Sciences, Jagiellonian University, Kraków 31-007, Poland., Cholewa-Waclaw J; High Content Screening Facility, Institute for Regeneration and Repair, The University of Edinburgh, Edinburgh EH16 4UU, UK., Yebra G; Roslin Institute, The University of Edinburgh, Midlothian EH25 9RG, UK., Chepsat J; University of Edinburgh Centre for Inflammation Research, Institute for Regeneration and Repair, Edinburgh EH16 4UU, UK., Jones GR; School of Infection and Immunity, University of Glasgow, Glasgow G12 8TA, UK., McHugh MP; Department of Clinical Microbiology, Royal Infirmary of Edinburgh, Edinburgh EH16 4SA, UK.; School of Medicine, University of St Andrews, St Andrews KY16 9TF, UK., Lynskey NN; Roslin Institute, The University of Edinburgh, Midlothian EH25 9RG, UK., Renshaw SA; Florey Institute, Bateson Centre and Division of Clinical Medicine, School of Medicine and Population Health, Sheffield S10 2RX, UK., Prajsnar TK; Department of Evolutionary Immunology, Institute of Zoology and Biomedical Research, Faculty of Biology, Jagiellonian University, Kraków 31-007, Poland., Baillie JK; University of Edinburgh Centre for Inflammation Research, Institute for Regeneration and Repair, Edinburgh EH16 4UU, UK.; Baillie-Gifford Pandemic Science Hub, Institute for Regeneration and Repair, The University of Edinburgh, Edinburgh EH16 4UU, UK.; Roslin Institute, The University of Edinburgh, Midlothian EH25 9RG, UK., Fitzgerald JR; Roslin Institute, The University of Edinburgh, Midlothian EH25 9RG, UK., Dockrell DH; University of Edinburgh Centre for Inflammation Research, Institute for Regeneration and Repair, Edinburgh EH16 4UU, UK.
Source: Science advances [Sci Adv] 2026 Feb 27; Vol. 12 (9), pp. eaea0375. Date of Electronic Publication: 2026 Feb 27.
Publication Type: Journal Article
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2375-2548 (Electronic) Linking ISSN: 23752548 NLM ISO Abbreviation: Sci Adv Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2375-2548
DOI:10.1126/sciadv.aea0375