Urinary aldosterone and tetrahydroaldosterone by LC-MS/MS with enzymatic hydrolysis: validation and age-stratified reference intervals.

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Title: Urinary aldosterone and tetrahydroaldosterone by LC-MS/MS with enzymatic hydrolysis: validation and age-stratified reference intervals.
Authors: Wijbenga-van der Kooi I; Department of Laboratory Medicine, University of Groningen, University Medical Center Groningen Groningen, The Netherlands., van Faassen M; Department of Laboratory Medicine, University of Groningen, University Medical Center Groningen Groningen, The Netherlands., Kerstens M; Department of Endocrinology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Kema IP; Department of Laboratory Medicine, University of Groningen, University Medical Center Groningen Groningen, The Netherlands., Vos MJ; Department of Laboratory Medicine, University of Groningen, University Medical Center Groningen Groningen, The Netherlands.
Source: Clinical chemistry and laboratory medicine [Clin Chem Lab Med] 2026 Mar 02; Vol. 64 (7), pp. 1614-1623. Date of Electronic Publication: 2026 Mar 02 (Print Publication: 2026).
Publication Type: Journal Article; Validation Study
Journal Info: Publisher: Walter De Gruyter Country of Publication: Germany NLM ID: 9806306 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 1437-4331 (Electronic) Linking ISSN: 14346621 NLM ISO Abbreviation: Clin Chem Lab Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1437-4331
DOI:10.1515/cclm-2025-1679