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Low-dose radiation generated ROS-activatable doxorubicin prodrug loaded liposome nanoparticles for triple-negative breast cancer treatment.

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Title: Low-dose radiation generated ROS-activatable doxorubicin prodrug loaded liposome nanoparticles for triple-negative breast cancer treatment.
Authors: Lim H; Department of Chemical and Biomolecular Engineering, Yonsei University, Seoul 03722, Republic of Korea; College of Pharmacy, Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul 03760, Republic of Korea., Moon Y; College of Pharmacy, Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul 03760, Republic of Korea., Han S; Department of Neurosurgery, College of Medicine, Yonsei University, Seoul 03722, Republic of Korea., Cho H; College of Pharmacy, Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul 03760, Republic of Korea; Noxpharm Co., LTD., Seoul 03759, Republic of Korea., Song S; College of Pharmacy, Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul 03760, Republic of Korea., Kim J; College of Pharmacy, Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul 03760, Republic of Korea., Goo J; Department of Chemical and Biomolecular Engineering, Yonsei University, Seoul 03722, Republic of Korea., Shim N; College of Pharmacy, Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul 03760, Republic of Korea., Guo L; School of Chemical Engineering, Sungkyunkwan University, Suwon 16419, Republic of Korea., Kim TI; School of Chemical Engineering, Sungkyunkwan University, Suwon 16419, Republic of Korea., Chang WS; Department of Neurosurgery, College of Medicine, Yonsei University, Seoul 03722, Republic of Korea. Electronic address: changws0716@yuhs.ac., Koh WG; Department of Chemical and Biomolecular Engineering, Yonsei University, Seoul 03722, Republic of Korea. Electronic address: wongun@yonsei.ac.kr., Kim K; College of Pharmacy, Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul 03760, Republic of Korea; Graduate Program in Innovative Biomaterials Convergence, Ewha Womans University, Seoul 03760, Republic of Korea. Electronic address: kimkm@ewha.ac.kr.
Source: Journal of controlled release : official journal of the Controlled Release Society [J Control Release] 2026 May 10; Vol. 393, pp. 114750. Date of Electronic Publication: 2026 Feb 27.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Publishers Country of Publication: Netherlands NLM ID: 8607908 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4995 (Electronic) Linking ISSN: 01683659 NLM ISO Abbreviation: J Control Release Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1873-4995
DOI:10.1016/j.jconrel.2026.114750