Case Report: Complete response to the concurrent neoadjuvant radiation therapy and pembrolizumab in a locally recurrent, chemotherapy-refractory undifferentiated pleomorphic sarcoma of bone.

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Title: Case Report: Complete response to the concurrent neoadjuvant radiation therapy and pembrolizumab in a locally recurrent, chemotherapy-refractory undifferentiated pleomorphic sarcoma of bone.
Authors: Patel BA; The University of Texas at Austin College of Natural Sciences, Austin, TX, United States., Smith JT; Department of Sarcoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States., Wangsiricharoen S; Pathology and Laboratory Medicine, Oregon Health and Science University, Portland, OR, United States., Wang WL; Department of Pathology, Division of Pathology/Lab Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, United States., Lin PP; Department of Orthopedic Oncology, Division of Surgery The University of Texas MD Anderson Cancer Center, Houston, TX, United States., Farooqi A; Division of Radiation Oncology The University of Texas MD Anderson Cancer Center, Houston, TX, United States., Nassif Haddad EF; Department of Sarcoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States., Ummed K; Georgia Cancer Specialists, Atlanta, GA, United States., Mericli AF; The University of Texas MD Anderson Cancer Center, Houston, TX, United States., Adelman DM; Department of Plastic Surgery The University of Texas MD Anderson Cancer Center, Houston, TX, United States., Livingston JA; Department of Sarcoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States., Conley AP; Department of Sarcoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.
Source: Frontiers in oncology [Front Oncol] 2026 Feb 12; Vol. 16, pp. 1645629. Date of Electronic Publication: 2026 Feb 12 (Print Publication: 2026).
Publication Type: Case Reports; Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101568867 Publication Model: eCollection Cited Medium: Print ISSN: 2234-943X (Print) Linking ISSN: 2234943X NLM ISO Abbreviation: Front Oncol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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Description
ISSN:2234-943X
DOI:10.3389/fonc.2026.1645629