Enhancing antioxidant capacity via NRF2 pathway activation to mitigate heat stress-induced oxidative damage in bovine granulosa cells, oocytes, and embryos.

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Title: Enhancing antioxidant capacity via NRF2 pathway activation to mitigate heat stress-induced oxidative damage in bovine granulosa cells, oocytes, and embryos.
Authors: Ramírez GG; Animal Reproduction and Biotechnology Laboratory (ARBL), Department of Biomedical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO, United States., Gad A; Animal Reproduction and Biotechnology Laboratory (ARBL), Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO, United States.; Department of Animal Production, Faculty of Agriculture, Cairo University, Giza, Egypt., Menjivar NG; Animal Reproduction and Biotechnology Laboratory (ARBL), Department of Biomedical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO, United States.; Stanford Children's Health. Lucile Packard Children's Hospital, Stanford Medicine, Fertility and Reproductive Health, Sunnyvale, CA, United States., Burlingham S; Cellular Engineering and Mechanobiology Laboratory (CEML), Translational Medicine Institute (TMI), Department of Mechanical Engineering, Colorado State University, Fort Collins, CO, United States., Cheng MH; Department of Electrical & Computer Engineering, Colorado State University, Fort Collins, CO, United States., Chen TW; Department of Electrical & Computer Engineering, Colorado State University, Fort Collins, CO, United States.; School of Biomedical Engineering, Colorado State University, Fort Collins, CO, United States., Ghosh S; Cellular Engineering and Mechanobiology Laboratory (CEML), Translational Medicine Institute (TMI), Department of Mechanical Engineering, Colorado State University, Fort Collins, CO, United States., Tesfaye D; Animal Reproduction and Biotechnology Laboratory (ARBL), Department of Biomedical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO, United States.
Source: Frontiers in cell and developmental biology [Front Cell Dev Biol] 2026 Feb 12; Vol. 14, pp. 1777760. Date of Electronic Publication: 2026 Feb 12 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Media S.A Country of Publication: Switzerland NLM ID: 101630250 Publication Model: eCollection Cited Medium: Print ISSN: 2296-634X (Print) Linking ISSN: 2296634X NLM ISO Abbreviation: Front Cell Dev Biol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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ISSN:2296-634X
DOI:10.3389/fcell.2026.1777760